Tolvaptan Impurity N1 CAS 247237-56-5
| CAS No. | 247237-56-5 |
| Molecular Formula | C10H10ClNO |
| Molecular Weight | 195.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Tolvaptan Impurity N1 (CAS 247237-56-5), a pharmacopoeial impurity reference standard (molecular formula C10H10ClNO, MW 195.65 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Tolvaptan Impurity N1 (C10H10ClNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 195.65 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tolvaptan Impurity N1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10ClNO |
| Molecular Weight | 195.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Tolvaptan Standards
- Tolvaptan Impurity 49 (CAS 116815-03-3)
- Tolvaptan Impurity 16 (CAS 160129-45-3)
- Tolvaptan Impurity 33 (CAS 1310357-40-4)
- Tolvaptan Impurity N2 (CAS 30459-70-2)
- Tolvaptan Impurity 17 (CAS 1975-51-5)
- Tolvaptan Impurity 73 (CAS 1316312-24-9)
- Tolvaptan Impurity 78 (CAS 1863916-82-8)
- Tolvaptan Impurity 74 (CAS CATO-C4X-195574)
Recommended Standards
- N-Allyl-4-chlorobenzamide (CAS 5866-99-9)
- 3-chloro-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one (CAS 86499-23-2)
- N-allyl-3-chlorobenzamide (CAS 35306-52-6)
- Baclofen EP Impurity A (CAS 22518-27-0)
- Goserelin EP Impurity I Acetate (CAS CATO-C4X-19209)
- Atorvastatin Impurity 79 (CAS CATO-C4X-113279)
- Ranitidine Impurity 23 (CAS CATO-C4X-137023)
- 2-Amino-N-cyclohexyl-6-(tert-pentyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (CAS 667412-93-3)
- Benzyl ((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)carbamate (Edoxaban Impurity) (CAS 2759920-22-2)
- 2,2,2-Trichloro-1-(5-nitro-1H-pyrrol-2-yl)ethanone (CAS 53391-41-6)
- 5-Bromo-1-(phenylsulfonyl)-1H-indazole (CAS 1001415-31-1)
- cis-{platinum(morpholine)(thiocyanate)2} (CAS 140242-96-2)
- 5-((2,5-Dichlorophenyl)thio)pentan-2-one (CAS 1153114-94-3)
- Semaglutide Impurity 14(Discontinued,See CPTD788307 ) (CAS CATO-C4X-222614)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com