Lesinurad Impurity 15 CAS 25033-19-6
| CAS No. | 25033-19-6 |
| Molecular Formula | C13H12 |
| Molecular Weight | 168.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lesinurad Impurity 15.
As a process- or degradation-related impurity, Lesinurad Impurity 15 (CAS 25033-19-6, C13H12) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Lesinurad Impurity 15 (C13H12) is characterized by an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H12 |
| Molecular Weight | 168.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
Related Lesinurad Standards
- Lesinurad Impurity 34 (CAS 878671-95-5)
- Lesinurad Impurity 4 (CAS 1547295-10-2)
- Lesinurad Impurity 21 (CAS 1533519-84-4)
- Lesinurad Impurity 12 (CAS 878671-96-6)
- Lesinurad Impurity 41 (CAS 1038366-57-2)
- Lesinurad Impurity 35 (CAS 1533519-86-6)
- Lesinurad Impurity 14 (CAS 1533519-93-5)
- Lesinurad Impurity 7 (CAS CATO-C4X-14787)
Recommended Standards
- Ethyl octa-4,7-dienoate (CAS 72276-09-6)
- methyl 1,4-dimethylcyclohex-3-ene-1-carboxylate (CAS 58911-05-0)
- Ethyl bicyclo[4.1.0]Heptane-7-carboxylate (CAS 52917-64-3)
- methyl 2-(2-methylcyclohexylidene)acetate (CAS 2208-95-9)
- Rivastigmine Impurity 44 (CAS 1285033-79-5)
- Ruxolitinib Impurity 171 (CAS 2201066-09-1)
- Calcipotriol Impurity 21 (CAS 143032-85-3)
- 5-methoxyimidazo[1,2-a]pyridine (CAS 31409-09-3)
- 2-((4R,5R)-2,2,5-Trimethyl-1,3-dioxan-4-yl)ethan-1-amine (CAS 2607047-86-7)
- Ethyl 2-acetamido-7-chloro-6-formylbenzo[b]thiophene-3-carboxylate (CAS 137987-74-7)
- Triphenylphosphine(1,5-cyclooctadiene)[1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene]iridium(I) hexafluorophosphate (CAS 1019853-00-9)
- 4-(Azepan-1-yl)-N-(4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)picolinamide (CAS 1421483-34-2)
- N-Butyl-6-(4-chlorophenoxy)hexan-1-amine (CAS 5564-49-8)
- Peptide Impurity 24 (CAS CATO-CPTD788824)
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