Propofol EP Impurity C CAS 25168-06-3

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.25168-06-3
Molecular FormulaC9H12O
Molecular Weight136.19 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Propofol EP Impurity C CAS 25168-06-3 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

CATO supplies Propofol EP Impurity C (CAS 25168-06-3), a pharmacopoeial impurity reference standard (molecular formula C9H12O, MW 136.19 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Propofol EP Impurity C (C9H12O) is characterized by a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC9H12O
Molecular Weight136.19 g/mol
Purity>95%
StorageStore at 2-8°C
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityStable under recommended storage conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1964

Related Propofol Standards

Recommended Standards

Why CATO?