Bis(4-fluorophenyl)phosphine CAS 25186-17-8
| CAS No. | 25186-17-8 |
| Molecular Formula | C12H9F2P |
| Molecular Weight | 222.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies Bis(4-fluorophenyl)phosphine (CAS 25186-17-8), a certified reference material (molecular formula C12H9F2P, MW 222.17 g/mol) for analytical method development and quality control.
Owing to organophosphorus functionality, fluorine substitution, an aromatic ring system, Bis(4-fluorophenyl)phosphine is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 222.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H9F2P |
| Molecular Weight | 222.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | F-containing |
Related Bis Standards
- 1-[(4-Fluorophenyl)methyl]imidazolidine-2,4,5-trione (CAS 105686-00-8)
- 1-(3-Fluorophenyl)-4-hydroxy-1h-pyrazole-3-carboxylic acid (CAS 1152511-49-3)
- 1-(2-Fluorophenyl)-4-hydroxy-1h-pyrazole-3-carboxylic acid (CAS 1152602-04-4)
- 1-(4-Fluorophenyl)-4-hydroxy-1h-pyrazole-3-carboxylic acid (CAS 1152602-19-1)
- 1-(4-Fluorophenyl)-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylic acid (CAS 1204296-62-7)
- 1-(4-Fluorophenyl)-5-oxo-4,5-dihydro-1H-pyrazole-4-carboxylic acid (CAS 1204297-01-7)
- 1-(2-Fluorophenyl)-5-oxo-4,5-dihydro-1H-pyrazole-4-carboxylic acid (CAS 1204297-73-3)
- 1-(4-Fluorophenyl)-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylic acid (CAS 1251384-99-2)
Recommended Standards
- 9-((2,3-Dimethylbutan-2-yl)oxy)-9-borabicyclo[3.3.1]nonane (CAS 89999-87-1)
- Methyl 4-fluoro-3-formyl-1H-indazole-6-carboxylate (CAS 885521-50-6)
- 8-(Trifluoromethyl)quinoline-4-carbonitrile (CAS 2055119-28-1)
- Methyl 5-(4-fluorophenyl)-1,2,4-oxadiazole-3-carboxylate (CAS 338960-42-2)
- Ethyl 6-oxo-6-(4-propoxyphenyl)hexanoate (CAS 898757-63-6)
- 2-Methyl-6-(methylthio)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1420296-82-7)
- 1-(Bromomethyl)-2-(4-chlorophenoxy)-4-fluorobenzene (CAS 1414958-69-2)
- 3-(1-Methyl-1H-benzo[d]imidazol-2-yl)propan-1-amine dihydrochloride (CAS 1245569-34-9)
- O-(3-methoxybenzyl)hydroxylamine hydrochloride (CAS 3839-39-2)
- Methyl 4-(pyrrolidin-1-ylmethyl)benzoate (CAS 160598-45-8)
- 6-(3,5-Dimethyl-1H-pyrazol-1-yl)-3-(4-methoxyphenyl)-7-(3-nitrophenyl)pyrazolo[1,5-a]pyrimidine (CAS 956755-29-6)
- N,N-Dimethyl-[4,4'-bipiperidine]-1-sulfonamide (CAS 1000958-59-7)
- 1-Methyl-4-nitro-1H-indole (CAS 91482-63-2)
- Semaglutide impurity 290 (CAS CATO-C4X-2226290)
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