Abrocitinib Impurity 57 CAS 252853-75-1
| CAS No. | 252853-75-1 |
| Molecular Formula | C11H14N4 |
| Molecular Weight | 202.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Abrocitinib Impurity 57 (C11H14N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Abrocitinib Impurity 57 (CAS 252853-75-1), a pharmacopoeial impurity reference standard (molecular formula C11H14N4, MW 202.26 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Abrocitinib Impurity 57 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H14N4 |
| Molecular Weight | 202.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
Related Abrocitinib Standards
- Abrocitinib Related Compound 3 (CAS 1622980-99-7)
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- Abrocitinib Impurity 19 (CAS CATO-C4X-288419)
- Abrocitinib Impurity 22 (CAS 91284-45-6)
- Abrocitinib Impurity 37 (CAS CATO-C4X-288437)
- Abrocitinib Impurity 28 (CAS 2215069-40-0)
- Abrocitinib Impurity 29 (CAS 2204276-97-9)
- Abrocitinib Desmethyl Impurity 7 (CAS 2920890-22-6)
Recommended Standards
- 3-(Trihydroxysilylpropyl)-1-propanesulphonic acid 3-(trihydroxysilyl)propane-1-sulfonic acid 70942-24-4 (CAS 70942-24-4)
- 4-(Thiophen-2-ylmethyl)benzaldehyde (CAS 1007847-72-4)
- 52943-14-3 3-Pyridinecarbonitrile, 2-(4-methyl-1-piperazinyl)- 5-23-03-00127 (Beilstein Handbook Reference) BRN 0615192 (Methyl-4 piperazinyl)-2 nicotinonitrile [French] 2-(4-Methyl-1-piperazinyl)-3-pyridinecarbonitrile Nicotinonitrile, 2-(4-methyl-1-piperazinyl)- (Methyl-4 piperazinyl)-2 nicotinonitrile (CAS 52943-14-3)
- 3,5-dimethylimidazo[2,1-b]thiazole-6-carboxylic acid (CAS 1007874-68-1)
- Diazepam Impurity 9 (CAS 17247-17-5)
- Metaraminol Impurity 77 (CAS CATO-C4X-225277)
- Rabeprazole Impurity 14 (CAS 924663-40-1)
- 3-(3-(4-Methyl-1,2,5-oxadiazol-3-yl)-1,2,4-oxadiazol-5-yl)propanoic acid (CAS 890095-35-9)
- Finerenone Impurity 196 (CAS CATO-C4X-2880196)
- n-(3-Aminophenyl)butanamide hydrochloride (CAS 1181458-24-1)
- Methyl 4-(2,4-dimethylphenyl)pyridine-2-carboxylate (CAS 1820649-68-0)
- 2-Bromo-5-nitrobenzenesulfonic acid (CAS 2459251-26-2)
- 3-Hydroxythieno[2,3-d]pyrimidine-2,4(1H,3H)-dione (CAS 53229-49-5)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com