Betamethasone Dipropionate EP Impurity H CAS 2575516-37-7
| CAS No. | 2575516-37-7 |
| Molecular Formula | C28H36BrFO7 |
| Molecular Weight | 583.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Betamethasone Dipropionate EP Impurity H.
CATO supplies Betamethasone Dipropionate EP Impurity H (CAS 2575516-37-7), a pharmacopoeial impurity reference standard (molecular formula C28H36BrFO7, MW 583.48 g/mol) used for the identification and quantification of trace impurities in APIs.
Betamethasone Dipropionate EP Impurity H (C28H36BrFO7) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Betamethasone Dipropionate EP Impurity H under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H36BrFO7 |
| Molecular Weight | 583.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | F/Br-containing |
Related Betamethasone Standards
- Betamethasone Dipropionate impurity 02 (CAS 1186048-34-9)
- Betamethasone β-D-Glucuronide (CAS 744161-79-3)
- Betamethasone impurity 46 (CAS 2409521-73-7)
- Betamethasone Dipropionate EP Impurity G (CAS 1186048-33-8)
- Betamethasone Valerate EP Impurity G (CAS CATO-C4X-143722)
- Betamethasone impurity 95 (CAS 1815577-58-2)
- Betamethasone Impurity 118 (CAS CATO-C4X-1437118)
- Betamethasone Impurity 110 (CAS CATO-C4X-1437110)
Recommended Standards
- [3-[2-(4-Benzoylpiperazin-1-yl)-2-oxoacetyl]-4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl]methyl Dihydrogen Phosphate (CAS 864953-29-7)
- ((Dimethylstannanediyl)bis(sulfanediyl))bis(ethane-2,1-diyl) dinonanoate (CAS 68298-40-8)
- Roflumilast Impurity 11 (CAS CATO-C4X-204711)
- ((Dimethylstannanediyl)bis(sulfanediyl))bis(ethane-2,1-diyl) bis(3,5,5-trimethylhexanoate) (CAS 67905-20-8)
- Bosutinib Impurity 13 (CAS CATO-C4X-184713)
- Linaclotide impurity 43 (CAS 1422389-15-8)
- Venetoclax Impurity 122 (CAS CATO-C4X-2495122)
- Ramelteon Impurity 21 (CAS 1092507-03-3)
- 1-(1H-benzo[d][1,2,3]triazol-1-yl)-N,N-dimethylmethanamine (CAS 57684-30-7)
- Ethyl 6-oxo-1-phenyl-4-(trifluoromethyl)-1,6-dihydropyridazine-3-carboxylate (CAS 477854-72-1)
- 6-Chloro-N-hydroxynicotinimidamide (CAS 468068-39-5)
- (2-(4-Chlorophenoxy)phenyl)methanamine (CAS 792158-57-7)
- 5-Oxo-4,5-dihydro-1H-pyrrolo[3,2-b]pyridine-3-carboxylic acid (CAS 1190321-95-9)
- Tau Peptide (337-368) (Repeat 4 Domain) trifluoroacetate salt (CAS 330456-27-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com