Upadacitinib Impurity 74 CAS 2650489-63-5
| CAS No. | 2650489-63-5 |
| Molecular Formula | C16H21NO4 |
| Molecular Weight | 291.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 291.34 g/mol gives Upadacitinib Impurity 74 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Upadacitinib Impurity 74 (CAS 2650489-63-5), a pharmacopoeial impurity reference standard (molecular formula C16H21NO4, MW 291.34 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Upadacitinib Impurity 74 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 291.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Upadacitinib Impurity 74 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H21NO4 |
| Molecular Weight | 291.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Nitrogen Atoms | 1 |
Related Upadacitinib Standards
- Upadacitinib Impurity 105 (CAS CATO-C4X-2405105)
- Upadacitinib Impurity 183 (CAS 2500633-42-9)
- Upadacitinib Impurity 147 (CAS CATO-C4X-2405147)
- Upadacitinib Impurity 153 (CAS CATO-C4X-2405153)
- Upadacitinib Impurity 156 (CAS CATO-C4X-2405156)
- Upadacitinib Impurity 157 (CAS CATO-C4X-2405157)
- Upadacitinib Impurity 150 (CAS CATO-C4X-2405150)
- Upadacitinib Impurity 2 (CAS 1201187-46-3)
Recommended Standards
- Ramelteon Impurity 51 (CAS 896736-20-2)
- Naproanilide (CAS 52570-16-8)
- Bisacodyl Impurity 9 (CAS 53555-73-0)
- Z-cyclohexyl-Gly-OH (CAS 69901-75-3)
- Cefdinir Impurity 24 (CAS CATO-C4X-121024)
- Ciprofloxacin Impurity 14 (CAS 103237-52-1)
- Epinephrine Impurity 91 (CAS 78995-74-1)
- Z-D-Arg(NO2)-OH (CAS 2279-08-5)
- (3S,6S)-3,6-bis(4-aminobutyl)piperazine-2,5-dione 2HCl (CAS 23409-32-7（free base）)
- Abrocitinib Impurity 3 (CAS 2204280-33-9)
- 3-(4-Acetyl-3,5-dimethyl-1h-pyrazol-1-yl)propanoic acid (CAS 890596-67-5)
- 5-((2-Chlorophenyl)(pyrrolidin-1-yl)methyl)-2-methylthiazolo[3,2-b][1,2,4]triazol-6-ol (CAS 869342-70-1)
- N-(3-Chloro-4-fluorophenyl)-2-fluorobenzamide (CAS 349128-65-0)
- Acetyl Tripeptide-1 (CAS 350595-76-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com