Nintedanib Impurity N5 CAS 262366-32-5
| CAS No. | 262366-32-5 |
| Molecular Formula | C29H31N5O2 |
| Molecular Weight | 481.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Nintedanib Impurity N5.
CATO supplies Nintedanib Impurity N5 (CAS 262366-32-5), a pharmacopoeial impurity reference standard (molecular formula C29H31N5O2, MW 481.59 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Nintedanib Impurity N5 (C29H31N5O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Nintedanib Impurity N5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C29H31N5O2 |
| Molecular Weight | 481.59 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 5 |
Related Nintedanib Standards
- Nintedanib Impurity 172 (CAS CATO-C4X-1814172)
- Nintedanib impurity 182 (CAS CATO-C4X-1814182)
- Nintedanib Impurity 8 (CAS 2410649-54-4)
- Nintedanib Impurity 177 (CAS CATO-C4X-1814177)
- Nintedanib Impurity 104 (CAS CATO-C4X-1814104)
- Nintedanib Impurity N8 (CAS 1139458-48-2)
- Nintedanib Impurity 103 (CAS CATO-C4X-1814103)
- Nintedanib Impurity N1 (CAS 894783-71-2)
Recommended Standards
- Dofequidar (CAS 129716-58-1)
- Telmisartan Impurity 102 (CAS CATO-C4X-1359102)
- 2-(3,5-Dimethyl-1H-pyrazole-1-carbonyl)-N-(4-methoxyphenyl)-N-methyl-4-phenylthiophene-3-sulfonamide (CAS 1173768-72-3)
- 15:0 Lyso PC (CAS 108273-89-8)
- Entacapone Impurity 22 (CAS 857629-78-8)
- Dequalinium impurity 34 (CAS CATO-C4X-193634)
- Linezolid Impurity 76 (CAS CATO-C4X-107376)
- 5-(3,4-Dimethoxyphenyl)oxazole-4-carboxylic acid (CAS 89205-08-3)
- Methyl 4-amino-3-chloro-5-methoxybenzoate (CAS 1427372-25-5)
- 1-(Tert-butyl) 3-methyl (3R,4R)-4-(6-chloro-5-pivalamidopyridin-2-yl)pyrrolidine-1,3-dicarboxylate (CAS 1217607-90-3)
- 2-(2-Bromo-4-ethylphenoxy)acetohydrazide (CAS 496029-30-2)
- 5-Allyl-1,3-difluoro-2-(pentyloxy)benzene (CAS 1443328-12-8)
- 2-Amino-1,2-diphenylethan-1-ol hydrochloride (CAS 5959-42-2)
- Liraglutide(13-31)TFA Salt (CAS CATO-C4X-19929)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com