Nintedanib Impurity N1 CAS 894783-71-2
| CAS No. | 894783-71-2 |
| Molecular Formula | C30H31N5O4 |
| Molecular Weight | 525.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Nintedanib Impurity N1 (CAS 894783-71-2), a pharmacopoeial impurity reference standard (molecular formula C30H31N5O4, MW 525.60 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Nintedanib Impurity N1 (C30H31N5O4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 18.0, corresponding to approximately 18 ring(s) or double-bond equivalent(s). With a molecular weight of 525.60 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Nintedanib Impurity N1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C30H31N5O4 |
| Molecular Weight | 525.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 5 |
Related Nintedanib Standards
- Nintedanib Impurity N2 (CAS CATO-C4X-12662)
- Nintedanib Impurity N3 (CAS CATO-C4X-12663)
- Nintedanib Impurity N7 (CAS 894783-61-0)
- Nintedanib Impurity N9 (CAS 334951-61-0)
- Nintedanib Impurity 103 (CAS CATO-C4X-1814103)
- Nintedanib Impurity 104 (CAS CATO-C4X-1814104)
- Nintedanib Impurity 105 (CAS CATO-C4X-1814105)
- Nintedanib E-Isomer (CAS 1160294-26-7)
Recommended Standards
- Ceftazidime Impurity 105 (CAS CATO-C4X-1212105)
- Imatinib (Piperidine)-N,N-DiOxide (CAS 571186-93-1)
- Ibrutinib Impurity 189 (CAS CATO-C4X-1064189)
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- Tolvaptan Impurity 109 (CAS CATO-C4X-1955109)
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- [3-(trifluoromethoxy)cyclohexyl]methanol (CAS 2231674-21-6)
- Phenethyl 2-(3-oxopiperazin-2-yl)acetate (CAS 1008015-33-5)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com