N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine CAS 267243-68-5
| CAS No. | 267243-68-5 |
| Molecular Formula | C21H23ClFN5O2 |
| Molecular Weight | 431.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 431.89 g/mol gives N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine (CAS 267243-68-5), molecular formula C21H23ClFN5O2 and molecular weight 431.89 g/mol, is a CATO reference standard with documented purity and traceability.
N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine (C21H23ClFN5O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H23ClFN5O2 |
| Molecular Weight | 431.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
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Recommended Standards
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- 5-[benzyl(4-methoxyphenyl)sulfamoyl]-2-chlorobenzoic acid (CAS 565198-70-1)
- Methyl 3-bromo-4-cyclopropylbenzoate (CAS 1131615-05-8)
- 4-methyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine (CAS 16462-94-5)
- Tert-butyl (1-acetyl-3,3-dimethylcyclobutyl)carbamate (CAS 2303004-06-8)
- Valsartan Impurity 127 (CAS CATO-C4X-1057127)
- 5-[4-(1,3-Dioxolan-2-yl)phenyl]-1H-indole (CAS 889954-45-4)
- 2,5-Dichloro-N-[4-(3-chlorothiophen-2-yl)-1,3-thiazol-2-yl]benzene-1-sulfonamide (CAS 376348-99-1)
- 3-Iodo-4-isopropylaniline (CAS 1369814-96-9)
- Ethyl 5-methoxy-2-nitrobenzoate (CAS 10399-67-4)
- Deoxydonepezil Hydrochloride (CAS 1034439-57-0)
- Delicious Peptide (bovine) (CAS 73984-05-1)
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