Ethyl 2-(1-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)-5-methylthiazole-4-carboxylate CAS 1823182-96-2
| CAS No. | 1823182-96-2 |
| Molecular Formula | C16H13ClF3N5O2S |
| Molecular Weight | 431.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 2-(1-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)-5-methylthiazole-4-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Ethyl 2-(1-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)-5-methylthiazole-4-carboxylate (CAS 1823182-96-2), a certified reference material (molecular formula C16H13ClF3N5O2S, MW 431.82 g/mol) for analytical method development and quality control.
The molecular framework of Ethyl 2-(1-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)-5-methylthiazole-4-carboxylate (C16H13ClF3N5O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H13ClF3N5O2S |
| Molecular Weight | 431.82 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-methoxyphenyl)-1H-pyrrole-2-sulfonamide (CAS 321433-66-3)
- 3-(3-(3-(2-Chloro-4-nitrophenoxy)propyl)ureido)benzene-1-sulfonyl fluoride (CAS 25240-52-2)
- 2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)ethyl 4-fluorobenzoate (CAS 338415-48-8)
- N-(3-chloro-4-fluorophenyl)-2-((3-cyano-6-ethyl-5-methyl-4-(trifluoromethyl)pyridin-2-yl)thio)acetamide (CAS 664999-23-9)
- 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(4-cyanophenoxy)phenyl)urea (CAS 1400989-25-4)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-1-[(1E)-{[(4-methoxyphenyl)methoxy]amino}methylidene]urea (CAS 321433-46-9)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-1-[(E)-[(3-ethoxy-4-hydroxyphenyl)methylidene]amino]urea (CAS 866149-29-3)
- N-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(pyridin-3-yloxy)phenyl)-1H-1,2,4-triazol-5-amine (CAS 877874-59-4)
Recommended Standards
- Ethyl N-[(2E)-2-({4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}methylidene)-2-cyanoacetyl]carbamate (CAS 338979-07-0)
- Albaconazole (CAS 187949-02-6)
- 5-((4-Chlorophenyl)sulfinyl)-N-(3-(trifluoromethyl)phenyl)-1,2,3-thiadiazole-4-carboxamide (CAS 306977-02-6)
- 3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-1-phenyl-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile (CAS 861209-33-8)
- 3-(Methoxycarbonyl)-6-phenylpicolinic acid (CAS 1443289-60-8)
- 2-(2-Aminobutan-2-yl)pyrimidin-4-amine (CAS 1339713-58-4)
- (2R)-1-Benzyl-5-oxo-N-(1-phenylethyl)pyrrolidine-2-carboxamide (CAS 1212481-86-1)
- Atorvastatin Impurity N2 (CAS 40281-50-3)
- Tert-butyl (2-amino-2-cyclopropylpropyl)carbamate (CAS 1269152-51-3)
- (E)-Octadec-9-en-1-amine hydrochloride (CAS 41130-29-4)
- 4-Hydroxy-2-(2-hydroxypropan-2-yl)-7-methyl-2H-furo[3,2-g]chromen-5(3H)-one (CAS 492-52-4)
- Sulfo-SDAD(Sulfo-NHS-SS-Diazirine) (sulfosuccinimidyl 2-[(4,4'-azipentanamido)ethyl]-1,3'-dithiopropionate] (CAS 1226983-32-9)
- (2-{2-[2-(2-aminoethyl)-4,5-dimethoxybenzyl]-4,5-dimethoxyphenyl}ethyl)amine dihydrochloride (CAS 1328085-12-6)
- Peptide-GMF (CAS CATO-CPTD788469)
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