3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-1-phenyl-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile CAS 861209-33-8
| CAS No. | 861209-33-8 |
| Molecular Formula | C21H13ClF3N3S |
| Molecular Weight | 431.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 431.86 g/mol gives 3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-1-phenyl-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-1-phenyl-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile (CAS 861209-33-8), molecular formula C21H13ClF3N3S and molecular weight 431.86 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-1-phenyl-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile (C21H13ClF3N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-1-phenyl-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H13ClF3N3S |
| Molecular Weight | 431.86 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-Chloro-2-(5-(4-(phenylthio)phenyl)-1H-pyrazol-1-yl)-5-(trifluoromethyl)pyridine (CAS 321998-12-3)
- 5-((6-Chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzo[d]imidazol-2-yl)oxy)-2-methylbenzoic acid (CAS 1219739-36-2)
- N-[(2-Chloro-6-fluorophenyl)methyl]-N-methyl-2,5-dioxo-4-phenyl-4-propyl-1-imidazolidineacetamide (CAS 852935-07-0)
- N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine (CAS 267243-68-5)
- N-(3-chloro-4-fluorophenyl)-2-((3-cyano-6-ethyl-5-methyl-4-(trifluoromethyl)pyridin-2-yl)thio)acetamide (CAS 664999-23-9)
- Ethyl 2-(1-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)-5-methylthiazole-4-carboxylate (CAS 1823182-96-2)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-methoxyphenyl)-1H-pyrrole-2-sulfonamide (CAS 321433-66-3)
- 3-(3-(3-(2-Chloro-4-nitrophenoxy)propyl)ureido)benzene-1-sulfonyl fluoride (CAS 25240-52-2)
Recommended Standards
- 5-((4-Chlorophenyl)sulfinyl)-N-(3-(trifluoromethyl)phenyl)-1,2,3-thiadiazole-4-carboxamide (CAS 306977-02-6)
- Ethyl 2-amino-4-(2-chloro-6-fluorophenyl)-5-oxo-4H,5H-thiochromeno[4,3-b]pyran-3-carboxylate (CAS 939894-07-2)
- Albaconazole (CAS 187949-02-6)
- 6-Amino-4-[[3-chloro-4-(2-pyridyloxy)phenyl]amino]-7-ethoxyquinoline-3-carbonitrile (CAS 1956340-48-9)
- Methyl 4-bromo-5-fluoro-2-methylbenzoate (CAS 1352889-89-4)
- 4-(Isobutylamino)-3-nitrobenzamide (CAS 851711-72-3)
- 1-Boc-3-ethynylpyrrolidine, 97% (CAS 287193-00-4)
- 2-(Methylamino)-2-[4-(trifluoromethyl)phenyl]acetic acid hydrochloride (CAS 1375471-43-4)
- N-propylcyclohexanamine hydrochloride (CAS 3592-82-3)
- 4-Methoxycycloheptan-1-one (CAS 17429-01-5)
- 2-Oxo-N-(p-tolyl)oxazolidine-3-sulfonamide (CAS 340185-08-2)
- Precocene 2 (CAS 644-06-4)
- 3-((5-Amino-1,3,4-thiadiazol-2-yl)thio)-N-cyclohexylpropanamide (CAS 1030772-85-0)
- Valosin Peptide (VQY), porcine (CAS 99510-37-9)
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