2-Chloro-3-(dimethylphosphinyl)-5-(trifluoromethyl)pyridine CAS 2703780-72-5
| CAS No. | 2703780-72-5 |
| Molecular Formula | C8H8ClF3NOP |
| Molecular Weight | 257.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-Chloro-3-(dimethylphosphinyl)-5-(trifluoromethyl)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
2-Chloro-3-(dimethylphosphinyl)-5-(trifluoromethyl)pyridine (CAS 2703780-72-5) is a high-purity analytical reference standard with the molecular formula C8H8ClF3NOP and a molecular weight of 257.58 g/mol.
Owing to an amide group, organophosphorus functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-Chloro-3-(dimethylphosphinyl)-5-(trifluoromethyl)pyridine is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 257.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H8ClF3NOP |
| Molecular Weight | 257.58 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-4-(dimethylphosphinyl)-6-(trifluoromethyl)pyridine (CAS 2680543-09-1)
- 2-Chloro-5-nitro-4-(2,2,2-trifluoroethoxy)pyrimidine (CAS 1699431-30-5)
- 2-Chloro-5-(2-ethoxy-1,1,2,2-tetrafluoroethyl)pyridine (CAS 2138526-11-9)
- 4-Chloro-6-(2,4-difluorophenoxy)pyrimidin-5-amine (CAS 1193217-94-5)
- Methyl 4-chloro-5,8-difluoroquinoline-2-carboxylate (CAS 219949-93-6)
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Recommended Standards
- 6-bromo-2-chloro-thieno[2,3-d]pyrimidine (CAS 1782440-51-0)
- 6-bromo-2-chloro-thieno[3,2-d]pyrimidine (CAS 1388050-36-9)
- 5-bromo-4-chlorothieno[2,3-d]pyrimidine (CAS 814918-95-1)
- 2-Amino-4-chloro-3-fluoro-5-(trifluoromethyl)benzoic acid (CAS 1698027-64-3)
- [1-(aminomethyl)-2-oxabicyclo[2.1.1]hexan-4-yl]methanol;hydrochloride (CAS 2138150-58-8)
- 3-(4-Bromophenyl)-1-(3,4-difluorophenyl)propan-1-one (CAS 898761-98-3)
- [(2R)-4,4-Difluoro-1-methylpyrrolidin-2-yl]methanamine dihydrochloride (CAS 2173052-69-0)
- tert-Butyl 3-bromo-4-methylbenzoate (CAS 160952-57-8)
- 1,1-dicyclopropylpropan-1-amine (CAS 2044902-40-9)
- [6-(4-fluorophenoxy)pyridin-2-yl]methanamine (CAS 1247710-87-7)
- 1-((3-Bromophenyl)sulfonyl)-4-ethylpiperazine (CAS 1004636-96-7)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com