Minocycline Impurity CAS 27179-27-7
| CAS No. | 27179-27-7 |
| Molecular Formula | C23H27N3O7 |
| Molecular Weight | 457.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Minocycline Impurity is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Minocycline Impurity (CAS 27179-27-7), molecular formula C23H27N3O7 and molecular weight 457.48 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Minocycline Impurity (C23H27N3O7) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 457.48 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H27N3O7 |
| Molecular Weight | 457.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 3 |
Related Minocycline Standards
- Minocycline Impurity N1 (CAS 10118-89-5)
- Minocycline EP Impurity A (HCl salt) (CAS 179471-96-6)
- Minocycline Amino Ethyl Derivative (CAS 4756-93-8)
- Minocycline EP Impurity A (CAS 43168-51-0)
- Minocycline (CAS 10118-90-8)
- Minocycline Impurity 70 (CAS CATO-C4X-169970)
- Minocycline EP Impurity E (CAS 864073-42-7)
- Minocycline Impurity 14 (CAS CATO-C4X-169914)
Recommended Standards
- Mitoxantrone Impurity 19 (CAS CATO-C4X-103419)
- H-Glu-Phe-Tyr-OH (CAS 70421-70-4)
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- Allyl 3-((3-(benzyloxy)-2-(ethoxycarbonyl)-4-oxopyridin-1(4H)-yl)amino)morpholine-4-carboxylate (CAS 2119729-44-9)
- tert-Butyl N-(2-aminocyclobutyl)carbamate (CAS 1378864-01-7)
- 1-(2-(Isopentylamino)-2-oxoethyl)-1H-pyrrole-3-carboxylic acid (CAS 1515398-63-6)
- Methyl 3-(hydroxymethyl)cyclobutane-1-carboxylate (CAS 89941-55-9)
- (1-(3-Chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazol-4-yl)methanol (CAS 618441-70-6)
- N-{5-Acetyl-6-[2-(dimethylamino)vinyl]-2-oxo-2H-pyran-3-yl}-3-(trifluoromethyl)benzenecarboxamide (CAS 1164529-66-1)
- tert-butyl N-(2-oxazol-4-ylethyl)carbamate (CAS 2694746-05-7)
- 3-Bromo-N-(2-(ethylamino)-2-oxoethyl)thiophene-2-carboxamide (CAS 1211373-97-5)
- 3-((3-Formylphenoxy)methyl)-4-methoxybenzaldehyde (CAS 438218-17-8)
- N-(2-(1H-indol-3-yl)ethyl)-2-(4-acetamidophenoxy)acetamide (CAS 946386-53-4)
- Semaglutide Impurity 8 (CAS CATO-C4X-22268)
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