Fosfomycin Impurity 48 CAS 27357-50-2 (Free Acid)
| CAS No. | 27357-50-2 (Free Acid) |
| Molecular Formula | 2*C3H7O4P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Fosfomycin Impurity 48 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Fosfomycin Impurity 48 (CAS 27357-50-2 (Free Acid)), a pharmacopoeial impurity reference standard (molecular formula C3H7O4PC8H11N, MW 259.24 g/mol) used for the identification and quantification of trace impurities in APIs.
Fosfomycin Impurity 48 (C3H7O4PC8H11N) contains an amide group, a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | 2*C3H7O4P 2*C8H11N |
| Molecular Weight | 259.24 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| Nitrogen Atoms | 1 |
Related Fosfomycin Standards
- Fosfomycin EP Impurity C (Barium Salt) (CAS 114252-50-5)
- Fosfomycin Open Ring Impurity A (CAS 1160525-87-0)
- Rac Fosfomycin-13C3 Benzylamine Salt (CAS 1216461-18-5)
- Fosfomycin Trometamol EP Impurity B (CAS 1262243-11-7)
- Fosfomycin Trometamol EP Impurity B TEA Salt (CAS 1262243-11-7(free base))
- Fosfomycin Trometamol EP Impurity D (CAS 1262243-12-8)
- Fosfomycin Trometamol EP Impurity D TEA salt(Discontinued,See C4X-13165) (CAS 1262243-12-8(Free Acid))
- Fosfomycin Trometamol EP Impurity D TFA salt (CAS 1262243-12-8(Free Base))
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- 1-{1-[(tert-butoxy)carbonyl]azetidin-3-yl}-1H-1,2,3-triazole-5-carboxylic acid (CAS 2092090-14-5)
- Cyclolinopeptide B (CAS 193139-41-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com