Ticagrelor Impurity 49 CAS 274693-54-8
| CAS No. | 274693-54-8 |
| Molecular Formula | C18H25NO6 |
| Molecular Weight | 351.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ticagrelor Impurity 49 (C18H25NO6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Ticagrelor Impurity 49 (CAS 274693-54-8) is a certified pharmaceutical impurity reference standard with the molecular formula C18H25NO6 and a molecular weight of 351.39 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ticagrelor Impurity 49 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H25NO6 |
| Molecular Weight | 351.39 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor Impurity 16 (CAS CATO-C4X-109316)
- Ticagrelor Impurity 192 (CAS 1628472-93-4)
- Ticagrelor EP Impurity A (CAS 1251765-07-7)
- Ticagrelor Impurity 81 (CAS CATO-C4X-109381)
- Ticagrelor Impurity 9 (CAS 1445580-43-7)
- Ticagrelor Impurity 82 (CAS 220241-60-1)
- Ticagrelor Impurity 10 (CAS 1402150-32-6)
- Ticagrelor impurity 169 (CAS CATO-C4X-1093169)
Recommended Standards
- 2,2-Dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azanonadecan-19-oic acid 876345-13-0 (CAS 876345-13-0)
- Z-Asp-OMPe (CAS 1998701-16-8)
- Jacobine (CAS 6870-67-3)
- Methyl [1-(3,4,5-trimethoxybenzoyl)piperidin-4-YL]acetate (CAS 946679-56-7)
- Ixazomib Impurity 14 (CAS 6287-38-3)
- Selexipag Impurity 33 (CAS CATO-C4X-196133)
- Viloxazine Impurity 11 (CAS 3033383-17-1)
- 1-Cyclopropyl-3-(5-(phenethylthio)-1,3,4-thiadiazol-2-yl)urea (CAS 1171721-55-3)
- 3-(Methylamino)adamantane-1-thiol (CAS 364342-53-0)
- Polaprezinc Impurity 15 (CAS CATO-C4X-182115)
- 3-(5-Methoxypyridin-3-yl)propanoic acid (CAS 1256825-62-3)
- 4-(3-Nitrophenyl)benzoic acid (CAS 5737-85-9)
- 2-(Bromomethyl)-4-(difluoromethyl)-6-iodo-3-methoxypyridine (CAS 1806883-62-4)
- Neuropeptide Y (13-36) (human, rat) (CAS 122341-40-6)
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