Ticagrelor Impurity 157 CAS 274693-55-9
| CAS No. | 274693-55-9 |
| Molecular Formula | C10H19NO4 |
| Molecular Weight | 217.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ticagrelor Impurity 157 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Ticagrelor Impurity 157 (CAS 274693-55-9, C10H19NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Ticagrelor Impurity 157 (C10H19NO4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C10H19NO4 |
| Molecular Weight | 217.26 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor Impurity 134 (CAS 2165881-71-8)
- Ticagrelor Related Compound 102 (CAS 2165387-08-4)
- Ticagrelor Related Compound 103 (CAS 2165566-46-9)
- Ticagrelor Impurity 23 (CAS CATO-C4X-109323)
- Ticagrelor Impurity 123 (CAS 33097-11-9)
- Ticagrelor Impurity 124 (CAS 1401318-10-2)
- Ticagrelor Impurity 121 (CAS 378236-67-0)
- Ticagrelor Impurity 88 (CAS 1006376-61-9)
Recommended Standards
- Agomelatine Impurity 43 (CAS CATO-C4X-110843)
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- N-[(S)-1-Carbethoxy-1-butyl]-L-alanine (CAS 82834-12-6)
- Ceritinib Impurity 17 (CAS CATO-C4X-1048917)
- Mivacurium chloride Impurity 55 (CAS CATO-C4X-137555)
- Roxithromycin EP Impurity J (CAS 134834-12-1)
- 2-((Decanoyloxy)methyl)-2-(hydroxymethyl)propane-1,3-diyl bis(decanoate) (CAS 68818-67-7)
- N-(2-(Indolin-1-yl)phenyl)pyrazine-2-carboxamide (CAS 1100121-56-9)
- Tert-butyl 4-(2-(2-bromo-4-fluorophenoxy)ethyl)piperazine-1-carboxylate (CAS 1227955-27-2)
- 3-(5-(2,5-Dichlorophenyl)furan-2-yl)-1-phenylprop-2-en-1-one (CAS 304896-43-3)
- 2-Phenylquinoline-8-thiol (CAS 15759-12-3)
- Methyl 5-bromo-2-(trifluoromethyl)thiazole-4-carboxylate (CAS 1449369-49-6)
- Acetyl decapeptide-3 (CAS 935288-50-9)
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