| CAS No. | 33097-11-9 |
| Molecular Formula | C6H4Cl2N2OS |
| Molecular Weight | 223.08 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 223.08 g/mol gives Ticagrelor Impurity 123 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Ticagrelor Impurity 123 (CAS 33097-11-9), a pharmacopoeial impurity reference standard (molecular formula C6H4Cl2N2OS, MW 223.08 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Ticagrelor Impurity 123 (C6H4Cl2N2OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ticagrelor Impurity 123 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C6H4Cl2N2OS |
| Molecular Weight | 223.08 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |