Ticagrelor Impurity 123 CAS 33097-11-9

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.33097-11-9
Molecular FormulaC6H4Cl2N2OS
Molecular Weight223.08 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ticagrelor Impurity 123 CAS 33097-11-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 223.08 g/mol gives Ticagrelor Impurity 123 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Ticagrelor Impurity 123 (CAS 33097-11-9), a pharmacopoeial impurity reference standard (molecular formula C6H4Cl2N2OS, MW 223.08 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Ticagrelor Impurity 123 (C6H4Cl2N2OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Ticagrelor Impurity 123 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H4Cl2N2OS
Molecular Weight223.08 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1966
Halogen ContentCl-containing
Nitrogen Atoms2
Sulfur Atoms1

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