Flupentixol Impurity 25 CAS 2748309-11-5
| CAS No. | 2748309-11-5 |
| Molecular Formula | C23H27F3N2O3S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 504.99 g/mol gives Flupentixol Impurity 25 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Flupentixol Impurity 25 (CAS 2748309-11-5, C23H27F3N2O3SHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Flupentixol Impurity 25 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 504.99 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H27F3N2O3S 2*HCl |
| Molecular Weight | 504.99 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Flupentixol Standards
- Flupentixol Impurity 21 (CAS 107265-28-1)
- Flupentixol Impurity 22 (CAS 129722-10-7)
- Flupentixol Impurity 1 (CAS 1535-17-7)
- Flupentixol Impurity 20 (CAS 1581762-35-7)
- Flupentixol Dihydrochloride EP Impurity G (CAS 1693-28-3)
- Flupentixol Impurity N96 (CAS 2244985-34-8)
- Flupentixol EP Impurity A Enantiomer (CAS 2340-57-0)
- Flupentixol EP Impurity A (CAS 23904-98-5)
Recommended Standards
- Mavacamten Impurity 9 (CAS 67463-81-4)
- Bisoprolol Impurity 92 (CAS CATO-C4X-124792)
- Naltrexone Impurity 23 (CAS 102272-79-7)
- 2-Amino-5-[butyl(methyl)amino]benzoic acid (CAS 875269-57-1)
- 5-Amino-1-(4-chloro-2-fluorophenyl)-3-methyl-1H-pyrazole-4-carbonitrile (CAS 2197063-20-8)
- 5-Amino-1H-indole-3-sulfonamide (CAS 132745-14-3)
- 2-(Aminomethyl)-5-(trifluoromethoxy)benzo[d]oxazole (CAS 1807067-46-4)
- 2,3-Dibromo-4,6-dimethylpyridine (CAS 610261-10-4)
- Methyl 3-{[(tert-butoxy)carbonyl](methyl)amino}-2-methylpropanoate (CAS 1248914-26-2)
- D-[Ser]8-Liraglutide (CAS CATO-C4X-199238)
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