Eltrombopag Impurity 99 CAS 277299-70-4

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.277299-70-4
Molecular FormulaC12H14N2O
Molecular Weight202.25 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Eltrombopag Impurity 99 CAS 277299-70-4 chemical structure

Description

CATO manufactures Eltrombopag Impurity 99 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

As a process- or degradation-related impurity, Eltrombopag Impurity 99 (CAS 277299-70-4, C12H14N2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Eltrombopag Impurity 99 (C12H14N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC12H14N2O
Molecular Weight202.25 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms2

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