Erdafitinib Impurity 10 CAS 2839751-66-3
| CAS No. | 2839751-66-3 |
| Molecular Formula | C10H14ClNO2 |
| Molecular Weight | 215.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 215.68 g/mol gives Erdafitinib Impurity 10 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Erdafitinib Impurity 10 (CAS 2839751-66-3), a pharmacopoeial impurity reference standard (molecular formula C10H14ClNO2, MW 215.68 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Erdafitinib Impurity 10 (C10H14ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 215.68 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Erdafitinib Impurity 10 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14ClNO2 |
| Molecular Weight | 215.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Erdafitinib Standards
- Erdafitinib Impurity 14 (CAS CATO-C4X-261614)
- Erdafitinib Impurity 1 (CAS 40534-39-2)
- Erdafitinib Impurity 3 (CAS 380639-03-2)
- Erdafitinib Impurity 12 (CAS CATO-C4X-261612)
- Erdafitinib Impurity 2 (CAS 123342-12-1)
- Erdafitinib Impurity 4 (CAS 2731009-66-6)
- Erdafitinib Impurity 13 (CAS 1346244-83-4)
- Erdafitinib Impurity 11 (CAS 1346243-54-6)
Recommended Standards
- 3-Chloro-2-(2-ethoxyethoxy)aniline 4141AF 946772-33-4 C10H14ClNO2 (CAS 946772-33-4)
- Atrazine (CAS 1912-24-9)
- 4029AF 5-Chloro-2-(3-methoxypropoxy)phenylamine 946682-50-4 C10H14ClNO2 (CAS 946682-50-4)
- ATRAZINE (CAS 102029-43-6)
- Tetrabenazine Impurity 15 (CAS 1256550-62-5)
- Norfloxacin EP Impurity A (CAS 68077-26-9)
- Palbociclib Impurity 33 (CAS 1651214-74-2)
- 1-Ethyl-1h-pyrazole-4-thiol (CAS 1343840-74-3)
- Sodium Valproate EP Impurity C (CAS 62391-99-5)
- Methyl 4-methoxy-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate (CAS 175202-30-9)
- 1-(4-Bromophenyl)cyclobutanemethanamine (CAS 1039932-36-9)
- 2-Benzyl-4-((2-(4-chlorophenyl)-2-methylpropoxy)methyl)furan (CAS 80843-64-7)
- 5-(5-(3,4-Dichlorophenoxy)pentyl)-N-methyl-1,3,4-thiadiazol-2-amine (CAS 87431-59-2)
- Tirzepatide Impurity 12 (CAS CATO-C4X-324012)
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