Erdafitinib Impurity 1 CAS 40534-39-2
| CAS No. | 40534-39-2 |
| Molecular Formula | C8H10N4 |
| Molecular Weight | 162.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Erdafitinib Impurity 1 (CAS 40534-39-2, C8H10N4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Erdafitinib Impurity 1 (C8H10N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Erdafitinib Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H10N4 |
| Molecular Weight | 162.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Nitrogen Atoms | 4 |
Related Erdafitinib Standards
- Erdafitinib Impurity 14 (CAS CATO-C4X-261614)
- Erdafitinib Impurity 10 (CAS 2839751-66-3)
- Erdafitinib Impurity 3 (CAS 380639-03-2)
- Erdafitinib Impurity 12 (CAS CATO-C4X-261612)
- Erdafitinib Impurity 2 (CAS 123342-12-1)
- Erdafitinib Impurity 4 (CAS 2731009-66-6)
- Erdafitinib Impurity 13 (CAS 1346244-83-4)
- Erdafitinib Impurity 11 (CAS 1346243-54-6)
Recommended Standards
- Tobramycin Impurity 29 (CAS CATO-C4X-220029)
- N-[2-[(2-Hydroxyethyl)amino]ethyl]glycine (CAS 58936-79-1)
- Tobramycin Impurity 14 (CAS 52850-89-2)
- (R,S)-Norcotinine (CAS 17708-87-1)
- Empagliflozin Impurity 115 (CAS CATO-C4X-1065115)
- Azelnidipine Impurity 5 (CAS 103426-18-2)
- Nintedanib Impurity 95 (CAS 16320-52-8)
- 5-(4-Chloro-2-fluorophenyl)furan-2-carboxylic acid (CAS 1094322-52-7)
- (1-(2-Methoxyphenyl)-1H-pyrazol-4-yl)boronic acid (CAS 2225172-55-2)
- ((1S,2S,4S)-Bicyclo[2.2.1]hept-5-en-2-yl)methanol (CAS 42070-82-6)
- 6-Bromo-5-(difluoromethyl)-2-methylpyridine-3-sulfonamide (CAS 1805443-04-2)
- 4-Bromo-1H-pyrrolo[2,3-b]pyridin-2(3H)-one (CAS 1086064-49-4)
- Ipriflavone Impurity 1 (CAS 3669-41-8)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com