Osimertinib Impurity 50 CAS 2850389-35-2
| CAS No. | 2850389-35-2 |
| Molecular Formula | C30H33N7O3 |
| Molecular Weight | 539.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 539.63 g/mol gives Osimertinib Impurity 50 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Osimertinib Impurity 50 (CAS 2850389-35-2) is a certified pharmaceutical impurity reference standard with the molecular formula C30H33N7O3 and a molecular weight of 539.63 g/mol.
Based on its molecular formula C30H33N7O3, Osimertinib Impurity 50 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 539.63 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Osimertinib Impurity 50 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C30H33N7O3 |
| Molecular Weight | 539.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Nitrogen Atoms | 7 |
Related Osimertinib Standards
- Osimertinib Impurity 112 (CAS 1932710-25-2)
- Osimertinib Impurity 31 (CAS CATO-C4X-204531)
- Osimertinib Impurity 25 (CAS CATO-C4X-204525)
- Osimertinib Impurity 24 (CAS CATO-C4X-204524)
- Osimertinib Impurity 57 (CAS CATO-C4X-204557)
- Osimertinib Impurity 42 (CAS 3086362-46-8)
- Osimertinib Impurity 37 (CAS CATO-C4X-204537)
- Osimertinib Impurity 80 (CAS CATO-C4X-204580)
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