Fluticasone Impurity 104 CAS CATO-C4X-1650104
| CAS No. | CATO-C4X-1650104 |
| Molecular Formula | C27H35F2NO6S |
| Molecular Weight | 539.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Fluticasone Impurity 104 (CAS CATO-C4X-1650104) is a certified pharmaceutical impurity reference standard with the molecular formula C27H35F2NO6S and a molecular weight of 539.63 g/mol.
Structurally, Fluticasone Impurity 104 (C27H35F2NO6S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 539.63 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H35F2NO6S |
| Molecular Weight | 539.63 g/mol |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Fluticasone Standards
- Fluticasone Impurity N3 (CAS 398454-98-3)
- Fluticasone Furoate (CAS 397864-44-7)
- Fluticasone Furoate EP Impurity I (CAS 3086156-07-9)
- Fluticasone Furoate D3 (CAS 397864-44-7(unlabelled))
- Fluticasone Furoate 11-Keto Impurity (CAS 397864-56-1)
- Fluticasone Impurity 75 (CAS CATO-C4X-165075)
- Fluticasone Impurity 35 (CAS CATO-C4X-165035)
- Fluticasone Furoate EP Impurity F (CAS CATO-C4X-165023)
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- 2-(Bromomethyl)benzo[d]oxazole-7-carbonyl chloride (CAS 1804105-13-2)
- 2-Bromo-4-(chloromethyl)-6-(difluoromethyl)pyridin-3-ol (CAS 1806856-19-8)
- Insulin Degludec Impurity 9 (CAS CATO-C4X-21579)
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