Dexamethasone Acetate EP Impurity F CAS 2884-51-7
| CAS No. | 2884-51-7 |
| Molecular Formula | C24H30O6 |
| Molecular Weight | 414.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Dexamethasone Acetate EP Impurity F (CAS 2884-51-7) is a certified pharmaceutical impurity reference standard with the molecular formula C24H30O6 and a molecular weight of 414.49 g/mol.
Dexamethasone Acetate EP Impurity F (C24H30O6) contains a flavonoid core, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H30O6 |
| Molecular Weight | 414.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Dexamethasone Standards
- Dexamethasone Acetate EP Impurity G (CAS 1597-78-0)
- Dexamethasone impurity 79 (CAS CATO-C4X-116579)
- Dexamethasone Impurity 24 (CAS 55879-47-5)
- Dexamethasone Impurity 97 (CAS CATO-C4X-116597)
- Dexamethasone Acid Ethyl Ester (CAS 2991360-83-7)
- Dexamethasone Impurity N1 (CAS 37926-77-5)
- Dexamethasone 17-Formyloxy-17-Acid (CAS 473273-04-0)
- Dexamethasone Impurity 61 (CAS CATO-C4X-116561)
Recommended Standards
- Methylprednisolone Acetate EP Impurity K (CAS 115321-98-7)
- Desonide Impurity 1(Desonide 9, 11-Epoxide) (CAS 39672-75-8)
- 54247-23-3 6,8-Dihydroxy-2,2,4,4-tetramethyl-5-(2-methylpropanoyl)-9-(propan-2-yl)-4,9-dihydro-1H-xanthene-1,3(2H)-dione DTXSID80432426 (CAS 54247-23-3)
- Reserpine Impurity 5 (CAS 2901-66-8)
- Penehyclidine Impurity 2 (CAS CATO-C3D-1445)
- Serotonin Impurity 3 (CAS CATO-C4X-25343)
- Orforglipron Impurity 146 (CAS CATO-C4X-3234146)
- 1-(6,7-Dihydro-[1,4]dioxino[2,3-d]pyrimidin-2-yl)propan-1-ol (CAS 946505-94-8)
- (S)-3-((2,4-Dichlorophenyl)sulfonyl)pyrrolidine hydrochloride (CAS 1417789-27-5)
- 1-[(1-ethyl-5-methyl-1H-pyrazol-4-yl)methyl]piperidine-4-carboxylic acid,2HCl (CAS 1431970-12-5)
- Chroman-2,3-dione (CAS 5818-89-3)
- 2-ethanesulfonamido-4-methoxybenzene-1-sulfonyl chloride (CAS 1423024-67-2)
- 4-Bromo-N-cyclopentyl-3-methylbenzamide (CAS 1020252-78-1)
- Semaglutide impurity 103 (CAS 1446013-07-5)
Why CATO?
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