Dexamethasone Acetate EP Impurity G CAS 1597-78-0
| CAS No. | 1597-78-0 |
| Molecular Formula | C24H31FO5 |
| Molecular Weight | 418.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dexamethasone Acetate EP Impurity G is closely related to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Dexamethasone Acetate EP Impurity G (CAS 1597-78-0) is a certified pharmaceutical impurity reference standard with the molecular formula C24H31FO5 and a molecular weight of 418.50 g/mol.
Based on its molecular formula C24H31FO5, Dexamethasone Acetate EP Impurity G contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 418.50 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dexamethasone Acetate EP Impurity G under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H31FO5 |
| Molecular Weight | 418.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone impurity 79 (CAS CATO-C4X-116579)
- Dexamethasone Acetate EP Impurity F (CAS 2884-51-7)
- Dexamethasone Impurity 24 (CAS 55879-47-5)
- Dexamethasone Impurity 97 (CAS CATO-C4X-116597)
- Dexamethasone Impurity 112 (CAS 134429-26-8)
- Dexamethasone Acid Ethyl Ester (CAS 2991360-83-7)
- Dexamethasone Impurity N1 (CAS 37926-77-5)
- Dexamethasone 17-Formyloxy-17-Acid (CAS 473273-04-0)
Recommended Standards
- 32638-88-3 Pyrogallol sulfonphthalein Benzenesulfonic acid, 2-(4,5,6-trihydroxy-3-oxo-3H-xanthen-9-yl)- Spiro(3H-2,1-benzoxathiole-3,9'-(9H)xanthene)-3',4',5',6'-tetrol, 1,1-dioxide AI3-63037 EINECS 251-134-3 (CAS 32638-88-3)
- Idebenone Impurity 7 (CAS 319906-76-8)
- m-PEG7-Ms (CAS 477775-57-8)
- Fluorometholone Acetate (CAS 3801-06-7)
- Aztreonam impurity 67 (CAS CATO-C4X-152267)
- Gefitinib Impurity 90 (CAS CATO-C4X-111790)
- Pentoxyverine Impurity 10 (CAS CATO-C4X-227010)
- Bifenox (Free Acid) (CAS 53774-07-5)
- 2-Chloro-N-(2,3-dichlorobenzyl)acetamide (CAS 172547-66-9)
- 4-Ethyl-5-(2-(p-tolyl)cyclopropyl)-4h-1,2,4-triazole-3-thiol (CAS 828280-55-3)
- (2-Methyl-5-(4-(methylsulfonyl)phenyl)-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl 4-fluorobenzoate (CAS 478043-41-3)
- 7-Bromoisochroman-1-one (CAS 1394180-31-4)
- 2-(1,3-Benzodioxo-5-yl)piperazine 2-(benzo[d][1,3]dioxol-5-yl)piperazine 65709-24-2 (CAS 65709-24-2)
- Des-Leu26-Tirzepatide (CAS CATO-CPTD788947)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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