Halometasone Impurity 8 CAS 28895-70-7
| CAS No. | 28895-70-7 |
| Molecular Formula | - |
| Molecular Weight | 469.88 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Halometasone Impurity 8 is closely related to a structurally diverse molecular composition in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Halometasone Impurity 8 (CAS 28895-70-7, N/A) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Halometasone Impurity 8 is supplied as a fully characterized reference material; its structural identity, assigned purity, and stability data are documented in the batch-specific Certificate of Analysis (COA).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Halometasone Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H24AClF2O6 |
| Molecular Weight | 469.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | F/Cl-containing |
Related Halometasone Standards
- Halometasone impurity 12 (CAS CATO-C4X-144612)
- Halometasone impurity 10 (CAS CATO-C4X-144610)
- Halometasone impurity 13 (CAS CATO-C4X-144613)
- Halometasone Impurity 5 (CAS CATO-C4X-14465)
- Halometasone Impurity N3 (CAS 23961-22-0)
- Halometasone Impurity 2 (CAS CATO-C4X-14462)
- Halometasone (CAS 50629-82-8)
- Halometasone Impurity 6 (CAS CATO-C4X-14466)
Recommended Standards
- N-(2-((4-chlorophenyl)sulfonyl)ethyl)-2-((3-(trifluoromethyl)phenyl)sulfonyl)acetamide (CAS 337923-11-2)
- Posaconazole Impurity 21 (CAS 175712-02-4)
- 2-(4-Chlorophenyl)-4-(1,3-dioxo-1,3-dihydro-2H-inden-2-ylidene)-6-(pyridin-2-yl)tetrahydropyrrolo[3,4-c]pyrrole-1,3(2H,3aH)-dione (CAS 321392-13-6)
- Methyl 6-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(methylsulfonamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (CAS 321430-47-1)
- Etoricoxib Impurity 24 (CAS 325855-71-8)
- Tegoprazan Impurity 121 (CAS CATO-C4X-2297121)
- Letermovir Impurity 65 (CAS CATO-C4X-291565)
- 4-[5-(4-Chlorobenzenesulfonyl)-1,2,3-thiadiazole-4-carbonyl]morpholine (CAS 306977-07-1)
- 6,7-Dimethoxy-1-methyl-3,4,6,7-tetrahydroisoquinoline (CAS 918665-57-3)
- Methyl 2-methoxy-5-methylisonicotinate (CAS 944838-10-2)
- (5-Methylimidazo[1,2-a]pyridin-2-yl)methanamine dihydrochloride (CAS 1284225-59-7)
- 5-Fluoro-2-methylanisole (CAS 95729-22-9)
- (E)-2-(3-(3-Methoxy-4-(prop-2-yn-1-yloxy)phenyl)acrylamido)benzoic acid (CAS 1001288-58-9)
- Peptide Impurity 41 (CAS CATO-CPTD788841)
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