N-(2-chloro-5-(5-methylbenzo[d]oxazol-2-yl)phenyl)-3-methyl-4-nitrobenzamide CAS 301354-47-2
| CAS No. | 301354-47-2 |
| Molecular Formula | C22H16ClN3O4 |
| Molecular Weight | 421.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
N-(2-chloro-5-(5-methylbenzo[d]oxazol-2-yl)phenyl)-3-methyl-4-nitrobenzamide (CAS 301354-47-2) is a high-purity analytical reference standard with the molecular formula C22H16ClN3O4 and a molecular weight of 421.83 g/mol.
The molecular framework of N-(2-chloro-5-(5-methylbenzo[d]oxazol-2-yl)phenyl)-3-methyl-4-nitrobenzamide (C22H16ClN3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H16ClN3O4 |
| Molecular Weight | 421.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
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Recommended Standards
- N-(5-(5-chlorobenzo[d]oxazol-2-yl)-2-methylphenyl)-3-methyl-4-nitrobenzamide (CAS 400740-94-5)
- Avanafil Impurity 129 (CAS CATO-C4X-1118129)
- 2-Amino-4-chloro-N-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]benzamide (CAS 206350-07-4)
- Tegoprazan Impurity 22 (CAS CATO-C4X-229722)
- 4-Fluoro-7-methyl-1H-pyrrolo[3,2-c]pyridine (CAS 1082042-22-5)
- 4-(4-(Benzyloxy)phenyl)-1h-pyrazole (CAS 1266690-18-9)
- 2,4-Bis(4-methyl-1-piperazinyl)-3H-1,5-benzodiazepine (CAS 733811-07-9)
- 2-Methoxy-3-palmitamidopropyl (2-(trimethylammonio)ethyl) phosphate (CAS 112989-00-1)
- (E)-3-allyl-2-thioxo-5-(3,4,5-trimethoxybenzylidene)thiazolidin-4-one (CAS 299904-48-6)
- Bis(1,1,1,3,3,3-hexafluoropropan-2-yl) carbonate (CAS 18925-66-1)
- Enzalutamide Impurity 56 (CAS CATO-C4X-101656)
- (5-(Difluoromethyl)-3-methyl-2-(trifluoromethoxy)pyridin-4-yl)methanamine (CAS 1804843-73-9)
- 2,4-Dimethylthiazole-5-boronic Acid Pinacol Ester (CAS 859833-13-9)
- Acetyl-Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 2022956-56-3)
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