2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-indol-3-yl}-N-[(1Z)-(methoxyamino)methylidene]acetamide CAS 303144-39-0
| CAS No. | 303144-39-0 |
| Molecular Formula | C18H14ClF3N4O2 |
| Molecular Weight | 410.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-indol-3-yl}-N-[(1Z)-(methoxyamino)methylidene]acetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 410.78 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-indol-3-yl}-N-[(1Z)-(methoxyamino)methylidene]acetamide (CAS 303144-39-0) is a high-purity analytical reference standard with the molecular formula C18H14ClF3N4O2 and a molecular weight of 410.78 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-indol-3-yl}-N-[(1Z)-(methoxyamino)methylidene]acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H14ClF3N4O2 |
| Molecular Weight | 410.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related chloro Standards
- 2-(((4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)amino)methylene)cyclohexane-1,3-dione (CAS 946387-28-6)
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Recommended Standards
- 1G-390S 321429-94-1 [(3Z)-5-methyl-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-1H-indol-3-ylidene]amino 2-chloroacetate (CAS 321429-94-1)
- Tolvaptan Impurity 118 (CAS CATO-C4X-1955118)
- 1,3-Diethyl 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-2-acetamidopropanedioate (CAS 306976-51-2)
- 1-(2-Chlorobenzamido)-3-cyanopropan-2-yl 3-(trifluoromethyl)benzoate (CAS 339101-94-9)
- 2-(6-Methyl-4-oxo-[1,2,3]triazolo[1,5-a]pyrazin-5(4H)-yl)acetic acid (CAS 1707594-76-0)
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