1-((4-Chloro-2-nitrophenyl)sulfonyl)spiro[indoline-3,2'-[1,3]dioxolan]-2-one CAS 866152-09-2
| CAS No. | 866152-09-2 |
| Molecular Formula | C16H11ClN2O7S |
| Molecular Weight | 410.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-((4-Chloro-2-nitrophenyl)sulfonyl)spiro[indoline-3,2'-[1,3]dioxolan]-2-one.
CATO supplies 1-((4-Chloro-2-nitrophenyl)sulfonyl)spiro[indoline-3,2'-[1,3]dioxolan]-2-one (CAS 866152-09-2), a certified reference material (molecular formula C16H11ClN2O7S, MW 410.79 g/mol) for analytical method development and quality control.
The molecular framework of 1-((4-Chloro-2-nitrophenyl)sulfonyl)spiro[indoline-3,2'-[1,3]dioxolan]-2-one (C16H11ClN2O7S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H11ClN2O7S |
| Molecular Weight | 410.79 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- Tolvaptan Impurity 118 (CAS CATO-C4X-1955118)
- 1G-390S 321429-94-1 [(3Z)-5-methyl-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-1H-indol-3-ylidene]amino 2-chloroacetate (CAS 321429-94-1)
- (2R,3S,4S,5R,6R)-2-(acetoxymethyl)-6-(2-chloroethoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 140428-85-9)
- 1,3-Diethyl 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-2-acetamidopropanedioate (CAS 306976-51-2)
- 2-Bromo-1-(2,2-diethoxyethoxy)-4-fluorobenzene (CAS 253429-18-4)
- (S)-4-Methoxy Propranolol (CAS 437999-45-6)
- 1-(4-Vinylbenzyl)piperidine (CAS 4072-75-7)
- 1-(3-Chlorophenyl)-2-cyclopropylethanone (CAS 1425367-32-3)
- (2S)-3-ethyl-1-methylazetidine-2-carboxylic acid (CAS 1860067-55-5)
- 7-isothiocyanato-3,4-dihydro-2H-1,5-benzodioxepine (CAS 1019442-90-0)
- 4-Penten-2-ol (CAS 625-31-0)
- Ethyl 5-cyano-1-(p-tolyl)-1H-pyrazole-3-carboxylate (CAS 121434-51-3)
- 3-amino-2-hydroxy-N-(pyridin-4-ylmethyl)propanamide dihydrochloride (CAS 2044834-43-5)
- Semaglutide Impurity 13 (CAS CATO-C4X-222613)
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