Tolvaptan Impurity 118 CAS CATO-C4X-1955118
| CAS No. | CATO-C4X-1955118 |
| Molecular Formula | C18H20ClN2O5P |
| Molecular Weight | 410.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Tolvaptan Impurity 118 (CAS CATO-C4X-1955118) is a certified pharmaceutical impurity reference standard with the molecular formula C18H20ClN2O5P and a molecular weight of 410.79 g/mol.
Structurally, Tolvaptan Impurity 118 (C18H20ClN2O5P) contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.5, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 410.79 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tolvaptan Impurity 118 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H20ClN2O5P |
| Molecular Weight | 410.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tolvaptan Standards
- Tolvaptan Impurity 124 (CAS CATO-C4X-1955124)
- Tolvaptan Impurity 89 (CAS 137977-65-2)
- Tolvaptan Impurity 129 (CAS 1448365-49-8)
- Tolvaptan Impurity 9 (CAS 1432725-23-9)
- Tolvaptan Impurity 80 (CAS CATO-C4X-195580)
- Tolvaptan Impurity 64 (CAS CATO-C4X-195564)
- Tolvaptan Impurity 76 (CAS 2458812-63-8)
- Tolvaptan Impurity 22 (CAS CATO-C4X-195522)
Recommended Standards
- 1-((4-Chloro-2-nitrophenyl)sulfonyl)spiro[indoline-3,2'-[1,3]dioxolan]-2-one (CAS 866152-09-2)
- N-(4-Chloro-3-pyridyl)-4-[[2,2-difluorobenzo[d][1,3]dioxol-5-yl]methyl]piperazine-1-carboxamide (CAS 1346528-50-4)
- 2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-indol-3-yl}-N-[(1Z)-(methoxyamino)methylidene]acetamide (CAS 303144-39-0)
- (2R,3S,4S,5R,6R)-2-(acetoxymethyl)-6-(2-chloroethoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 140428-85-9)
- Apremilast Impurity 86 (CAS 106860-70-2)
- Cetirizine EP Impurity E(Dihydrochloride) (CAS 83881-56-5)
- Diacerein Impurity 20 (CAS 159898-12-1)
- 2-((1-Methyl-1H-tetrazol-5-yl)thio)-N-(6-(4-methylpiperidin-1-yl)pyrimidin-4-yl)acetamide (CAS 1396866-31-1)
- 6-(Trifluoromethyl)-1H-pyrazolo[4,3-b]pyridin-3-amine (CAS 1211536-39-8)
- N-(4-(N-(Thiazol-2-yl)sulfamoyl)phenyl)-2-(thiophene-3-carboxamido)oxazole-4-carboxamide (CAS 1421484-77-6)
- 3-Chloro-N,N-dimethyl-1H-pyrazole-1-sulfonamide (CAS 458543-77-6)
- O-Desmethyl Mebeverine Acid (CAS 586357-02-0)
- 3-(1-(3-Isopropylphenyl)-2,5-dimethyl-1h-pyrrol-3-yl)acrylic acid (CAS 924858-64-0)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com