3-Chloro-2-[(pyridin-2-ylsulfanyl)methyl]-5-(trifluoromethyl)pyridine CAS 303147-81-1
| CAS No. | 303147-81-1 |
| Molecular Formula | C12H8ClF3N2S |
| Molecular Weight | 304.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Chloro-2-[(pyridin-2-ylsulfanyl)methyl]-5-(trifluoromethyl)pyridine (C12H8ClF3N2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
3-Chloro-2-[(pyridin-2-ylsulfanyl)methyl]-5-(trifluoromethyl)pyridine (CAS 303147-81-1), molecular formula C12H8ClF3N2S and molecular weight 304.72 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Chloro-2-[(pyridin-2-ylsulfanyl)methyl]-5-(trifluoromethyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8ClF3N2S |
| Molecular Weight | 304.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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- Semaglutide Impurity 15 (CAS CATO-C4X-222615)
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