4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)aniline CAS 581792-83-8
| CAS No. | 581792-83-8 |
| Molecular Formula | C12H8ClF3N2S |
| Molecular Weight | 304.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)aniline (CAS 581792-83-8), molecular formula C12H8ClF3N2S and molecular weight 304.72 g/mol, is a CATO reference standard with documented purity and traceability.
4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)aniline (C12H8ClF3N2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)aniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8ClF3N2S |
| Molecular Weight | 304.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 1-(4-Chloro-5-(4-(trifluoromethyl)phenyl)thiophen-2-yl)ethan-1-one (CAS 1305253-00-2)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)aniline (CAS 338406-70-5)
- 3-Chloro-2-[(pyridin-2-ylsulfanyl)methyl]-5-(trifluoromethyl)pyridine (CAS 303147-81-1)
- 8-(2-Chloro-4,5-difluorophenyl)-8-oxooctanoic acid (CAS 951891-55-7)
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Recommended Standards
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- 6-Bromo-4-iodonicotinonitrile (CAS 1061357-87-6)
- (4-Fluoro-2,6-dimethoxyphenyl)boronic acid (CAS 512186-38-8)
- 2-Propenoic acid, 2-methyl-, octadecyl ester, polymer with N-(1,1-dimethyl-3-oxobutyl)-2-propenamide and 2-propenenitrile (CAS 67953-84-8)
- 3-(Bromomethyl)cyclobutanone (CAS 463961-43-5)
- 2,2-Difluoroethyl (2,2,3,3,4,4,5,5,6,6,6-undecafluorohexyl) carbonate (CAS 1980035-41-3)
- 1-(4-Ethylcyclohexyl)ethan-1-one (CAS 67580-44-3)
- 1-(1,3-Dioxan-5-yl)-N,N-dimethyl-1-(pyridin-3-yl)methanamine (CAS 62938-80-1)
- Semaglutide Impurity 177 (CAS CATO-C4X-2226177)
Why CATO?
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