Famotidine Impurity 54 CAS CATO-C4X-139254
| CAS No. | CATO-C4X-139254 |
| Molecular Formula | C3H8ClN3O2S |
| Molecular Weight | 185.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 185.63 g/mol gives Famotidine Impurity 54 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Famotidine Impurity 54 (CAS CATO-C4X-139254, C3H8ClN3O2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Famotidine Impurity 54 (C3H8ClN3O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Famotidine Impurity 54 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C3H8ClN3O2S |
| Molecular Weight | 185.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Famotidine Standards
- Famotidine Impurity 45 (CAS 1644079-90-2)
- Famotidine impurity 63 (CAS CATO-C4X-139263)
- Famotidine Impurity 78 (CAS 88068-99-9)
- Famotidine Impurity 79 (CAS CATO-C4X-139279)
- Famotidine Impurity 50 (CAS 95853-51-3)
- Famotidine impurity 69 (CAS 850864-53-8)
- Famotidine Impurity 02 (CAS 81152-53-6)
- Famotidine Impurity 27 (CAS 1378820-83-7)
Recommended Standards
- 5-Chlorobenzo[d]isothiazol-3(2H)-one (CAS 4337-43-3)
- Tizanidine impurity 34 (CAS CATO-C4X-144534)
- Ticagrelor Impurity N1 (CAS 2227766-79-0)
- Tizanidine EP Impurity E (CAS 30536-19-7)
- Prusogliptin Impurity 6 (CAS CATO-C4X-32846)
- Abiraterone Impurity 12 (CAS CATO-C4X-107012)
- Tenofovir disoproxil Impurity 54 (CAS 1878175-76-8)
- Torasemide impurity 39 (CAS CATO-C4X-183639)
- 1-Cyclopropyl-6,7-difluoro-5-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 119915-47-8)
- 4-Acetamido-3-fluorobenzoic acid (CAS 713-11-1)
- 3-(Aminomethyl)pyridin-4-amine (CAS 158531-09-0)
- 1-(Piperazin-1-yl)but-2-en-1-one (CAS 412334-55-5)
- Oxymetazoline EP Impurity E (CAS 55699-10-0)
- Tirzepatide Impurity 61 (CAS CATO-C4X-324061)
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