Vonoprazan Impurity 281 CAS 3058423-29-0
| CAS No. | 3058423-29-0 |
| Molecular Formula | C23H21F2N3 |
| Molecular Weight | 377.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Vonoprazan Impurity 281 (CAS 3058423-29-0), a pharmacopoeial impurity reference standard (molecular formula C23H21F2N3, MW 377.43 g/mol) used for the identification and quantification of trace impurities in APIs.
Vonoprazan Impurity 281 (C23H21F2N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Vonoprazan Impurity 281 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H21F2N3 |
| Molecular Weight | 377.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Vonoprazan Standards
- Vonoprazan Impurity 260-D3 (CAS CATO-C4X-1020260)
- Vonoprazan Impurity 224 (CAS CATO-C4X-1020224)
- Vonoprazan Impurity 190 (CAS CATO-C4X-1020190)
- Vonoprazan Impurity 257 (CAS CATO-C4X-1020257)
- Vonoprazan Impurity 292 (CAS CATO-C4X-1020292)
- Vonoprazan Impurity N18 (CAS 2389131-50-2)
- Vonoprazan Impurity 195 (CAS 1126403-28-8)
- Vonoprazan Impurity C295 (CAS 928325-68-2)
Recommended Standards
- tert-Butyl5-(methoxymethoxy)-4-oxospiro[chroman-2,4-piperidine]-1-carboxylate (CAS 911227-80-0)
- Rosuvastatin Impurity 136 (CAS 890028-66-7)
- tert-Butyl 4-(((benzyloxy)carbonyl)amino)-4-carbamoylpiperidine-1-carboxylate (CAS 288154-17-6)
- Terbutaline impurity 86 (CAS CATO-C4X-118386)
- Empagliflozin Impurity 53 (CAS CATO-C4X-106553)
- Deoxycholic acid Impurity 24 (CAS 73505-50-7)
- Ibuprofen impurity 144 (CAS CATO-C4X-1082144)
- 4-Methylpent-4-en-1-ol (CAS 22508-64-1)
- 1-(5-Bromo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone (CAS 1375303-71-1)
- 4-(2-(((Benzyloxy)carbonyl)amino)ethyl)benzoic acid (CAS 121632-81-3)
- Methyl (E)-2-(N'-(1,3,4-thiadiazol-2-yl)formimidamido)thiophene-3-carboxylate (CAS 338777-33-6)
- 1-(3-Bromopropoxy)-4-methoxybenzene (CAS 6267-37-4)
- 2-(2-(m-Tolyl)propan-2-yl)-1,3,4-oxadiazole (CAS 1026444-42-7)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com