Spironolactone EP Impurity D CAS 3079028-52-4

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.3079028-52-4
Molecular FormulaC24H32O4S2
Molecular Weight448.64 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Spironolactone EP Impurity D CAS 3079028-52-4 chemical structure

Description

The occurrence of Spironolactone EP Impurity D is closely related to a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Spironolactone EP Impurity D (CAS 3079028-52-4), a pharmacopoeial impurity reference standard (molecular formula C24H32O4S2, MW 448.64 g/mol) used for the identification and quantification of trace impurities in APIs.

Structurally, Spironolactone EP Impurity D (C24H32O4S2) contains a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 448.64 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Spironolactone EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC24H32O4S2
Molecular Weight448.64 g/mol
Purity>95%
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2005
Sulfur Atoms2

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