Spironolactone EP Impurity G CAS 880106-10-5
| CAS No. | 880106-10-5 |
| Molecular Formula | C24H32O5S |
| Molecular Weight | 432.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Spironolactone EP Impurity G is closely related to a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Spironolactone EP Impurity G (CAS 880106-10-5) is a certified pharmaceutical impurity reference standard with the molecular formula C24H32O5S and a molecular weight of 432.57 g/mol.
Spironolactone EP Impurity G (C24H32O5S) contains a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Spironolactone EP Impurity G under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H32O5S |
| Molecular Weight | 432.57 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Sulfur Atoms | 1 |
Related Spironolactone Standards
- Spironolactone Impurity 20 (CAS CATO-C4X-134520)
- Spironolactone-d7(Major) (CAS CATO-CCAD302541)
- Spironolactone EP Impurity I (CAS CATO-C4X-13459)
- Spironolactone D3 (CAS 52-01-7 (Unlabeled))
- Spironolactone EP Impurity E (CAS 33784-05-3)
- Spironolactone (CAS 52-01-7)
- Spironolactone EP Impurity D (CAS 3079028-52-4)
- Spironolactone EP Impurity A (CAS 132458-33-4)
Recommended Standards
- 1-(2-(Benzhydryloxy)ethyl)-4-(3-(4-fluorophenyl)propyl)piperazine (CAS 76778-23-9)
- Relebactam Impurity 121 (CAS CATO-C4X-2144121)
- Ranolazine-d (CAS 1092804-87-9)
- Adaplene-D6 Methyl Ester (CAS 1330264-23-7)
- Misoprostol EP Impurity D (Mixture of E/Z-Isomers) (CAS 1331639-92-9)
- Atrasentan Impurity 166 (CAS 1059043-38-7)
- Clopidogrel Impurity 122 (CAS CATO-C4X-1029122)
- 1-(6-(4-Chlorophenyl)-2-methylpyridin-3-yl)ethanol (CAS 1432225-25-6)
- 3-Chloro-4-(trifluoromethyl)benzoyl chloride (CAS 1092460-77-9)
- 6-Bromo-2-fluoro-3-(trifluoromethyl)aniline (CAS 1217303-26-8)
- 4-Borono-2-methylbenzoic acid (CAS 191089-06-2)
- (1,2-Dichloro-1,2,2-trifluoroethyl)cyclohexane (CAS 219904-98-0)
- 4,7-Dimethoxy-N-(3-morpholinopropyl)benzo[d]thiazol-2-amine (CAS 1105188-79-1)
- Staphylococcus Aureus Protein A (SpA)-Derived Peptide (H-2228.0005) (CAS 144979-26-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com