Allopurinol EP Impurity E CAS 31055-19-3
| CAS No. | 31055-19-3 |
| Molecular Formula | C7H9N3O3 |
| Molecular Weight | 183.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 183.16 g/mol gives Allopurinol EP Impurity E distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Allopurinol EP Impurity E (CAS 31055-19-3), a pharmacopoeial impurity reference standard (molecular formula C7H9N3O3, MW 183.16 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Allopurinol EP Impurity E (C7H9N3O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Allopurinol EP Impurity E meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H9N3O3 |
| Molecular Weight | 183.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 3 |
Related Allopurinol Standards
- Allopurinol impurity 22 (CAS CATO-C4X-145822)
- Allopurinol impurity 29 (CAS CATO-C4X-145829)
- Allopurinol EP Impurity C (CAS 1346604-13-4)
- Allopurinol impurity 16 (CAS CATO-C4X-145816)
- Allopurinol impurity 20 (CAS CATO-C4X-145820)
- Allopurinol impurity 11 (CAS CATO-C4X-145811)
- Allopurinol impurity 23 (CAS CATO-C4X-145823)
- Allopurinol impurity 26 (CAS CATO-C4X-145826)
Recommended Standards
- Sunitinib Impurity 5 (CAS 5434-29-7)
- Entacapone impurity 38 (CAS CATO-C4X-162938)
- Ornidazole Impurity 9 (CAS 16773-51-6)
- Bosutinib Impurity 33 (CAS 709-09-1)
- Lubiprostone Impurity 13 (CAS CATO-C4X-113613)
- Bepotastine Impurity 30 (CAS CATO-C4X-183930)
- Liothyronine Impurity 2 (CAS 70-78-0)
- 2,4-Dimethoxy-6-methyl benzoic acid, 97% (CAS 3686-57-5)
- 2-Bromo-1-methoxy-4-(methoxymethyl)benzene (CAS 111210-24-3)
- Boc-3-iodo-<SC>D</SC>-Ala-OMe (CAS 170848-34-7)
- 1-(Cyclopropylmethyl)-3,5-diphenyl-1H-benzo[d]imidazol-2(3H)-one (CAS 1359758-29-4)
- [1,2,4]Triazolo[4,3-a]quinoxalin-4(5H)-one (CAS 91895-36-2)
- 2-(4-Carbamoylphenyl)propanoic acid (CAS 1624261-50-2)
- Cholecystokinin Octapeptide (1-4) (desulfated) (CAS 80790-40-5)
Why CATO?
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