Irinotecan EP Impurity L Hydrochloride Trihydrate CAS 3105679-83-9
| CAS No. | 3105679-83-9 |
| Molecular Formula | C33H38N4O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Irinotecan EP Impurity L Hydrochloride Trihydrate.
As a process- or degradation-related impurity, Irinotecan EP Impurity L Hydrochloride Trihydrate (CAS 3105679-83-9, C33H38N4O6HClH2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Irinotecan EP Impurity L Hydrochloride Trihydrate (C33H38N4O6HClH2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Irinotecan EP Impurity L Hydrochloride Trihydrate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C33H38N4O6 HCl 3*H2O |
| Molecular Weight | 641.16 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Irinotecan Standards
- Irinotecan Hydrochloride (CAS 100286-90-6)
- Irinotecan Impurity 70 (CAS 100286-91-7)
- Irinotecan Impurity 69 (CAS 100286-92-8)
- Irinotecan Impurity 72 (CAS 100286-93-9)
- Irinotecan Impurity 71 (CAS 100286-94-0)
- Irinotecan Impurity N1 (CAS 1026078-50-1)
- Irinotecan EP Impurity A (CAS 103816-16-6)
- Irinotecan Impurity 14 (CAS 110351-94-5)
Recommended Standards
- Imatinib EP Impurity J (CAS 571186-91-9)
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- Ethyl 7-(3-methoxyphenyl)-7-oxoheptanoate (CAS 122115-58-6)
- 4-(3-Methoxyphenyl)picolinic acid (CAS 1255637-89-8)
- [2-(difluoromethoxy)-3-methoxyphenyl]methanamine hydrochloride (CAS 1311317-05-1)
- 1,2,3-Trichloropropene (cis- and trans- mixture) (CAS 96-19-5)
- Des-Tyr10-Tirzepatide (CAS CATO-CPTD788680)
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