Empagliflozin Impurity 03 CAS 312749-31-8
| CAS No. | 312749-31-8 |
| Molecular Formula | C13H8BrClO |
| Molecular Weight | 295.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Empagliflozin Impurity 03 (CAS 312749-31-8) is a certified pharmaceutical impurity reference standard with the molecular formula C13H8BrClO and a molecular weight of 295.56 g/mol.
Owing to a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system, Empagliflozin Impurity 03 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 295.56 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H8BrClO |
| Molecular Weight | 295.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 90 (CAS 620621-48-9)
- Empagliflozin impurity 56 (CAS 1628918-33-1)
- Empagliflozin impurity 260 (CAS CATO-C4X-1065260)
- Empagliflozin Impurity 2 (CAS 2517968-35-1)
- Empagliflozin Impurity 154 (CAS 2452301-22-1)
- Empagliflozin Impurity 310 (CAS CATO-C4X-1065310)
- Empagliflozin Impurity 4 (CAS 2770456-61-4)
- Empagliflozin Impurity 46 (CAS CATO-C4X-106546)
Recommended Standards
- 2-Bromo-2-chlorobenzophenone (CAS 525561-42-6)
- N-(3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide (CAS 1025718-81-3)
- (4-Bromophenyl)(4-chlorophenyl)methanone (CAS 27428-57-5)
- 5-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 1154740-68-7)
- Lornoxicam impurity 90 (CAS CATO-C4X-201690)
- Gefitinib Impurity 4 (CAS 2089650-13-3)
- Venetoclax Impurity 21 (CAS CATO-C4X-249521)
- N-Benzyl-4-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]benzamide (CAS 1119450-84-8)
- Butyl[(2,3-dichlorophenyl)methyl]amine (CAS 774556-27-3)
- 3-Ethyl 7-methyl 4-aminoquinoline-3,7-dicarboxylate (CAS 1171763-34-0)
- Tetracyclohexyltin, 99% (CAS 1449-55-4)
- 3-(pyrrolidine-1-sulfonyl)-2,5-dihydro-1$l^{6}-thiophene-1,1-dione (CAS 1384428-10-7)
- 3-Cyclobutylpropanal (CAS 18543-43-6)
- D-Ile27-Tirzepatide (CAS CATO-CPTD788907)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com