Estazolam Impurity 9 CAS 31709-27-0
| CAS No. | 31709-27-0 |
| Molecular Formula | C15H10ClN3O |
| Molecular Weight | 283.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Estazolam Impurity 9.
CATO supplies Estazolam Impurity 9 (CAS 31709-27-0), a pharmacopoeial impurity reference standard (molecular formula C15H10ClN3O, MW 283.71 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C15H10ClN3O, Estazolam Impurity 9 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 283.71 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10ClN3O |
| Molecular Weight | 283.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Estazolam Standards
Recommended Standards
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- (4-Methyl-2-((tetrahydrofuran-2-yl)methoxy)phenyl)methanamine (CAS 1250081-20-9)
- Semaglutide (CAS CATO-C4X-2226105)
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