Estazolam Impurity 7 CAS 163167-55-3
| CAS No. | 163167-55-3 |
| Molecular Formula | C16H11ClN4 |
| Molecular Weight | 294.74 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Estazolam Impurity 7 (CAS 163167-55-3), a pharmacopoeial impurity reference standard (molecular formula C16H11ClN4, MW 294.74 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Estazolam Impurity 7 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 294.74 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H11ClN4 |
| Molecular Weight | 294.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Estazolam Standards
Recommended Standards
- Letrozole Impurity 35 (CAS CATO-C4X-182935)
- 6-Chloro-9a-(2-fluoroethyl)-7-methoxy-9,9a-dihydro-1H-fluoren-3(2H)-one (CAS 1039456-85-3)
- Suvorexant Impurity 46 (CAS CATO-C4X-181246)
- (4-Chlorophenyl)(3-methanesulfonylphenyl)methanone (CAS 1097140-03-8)
- Baricitinib Impurity 118 (CAS CATO-C4X-2260118)
- Ticagrelor Impurity 190 (CAS 2880337-24-4)
- Camptothecin impurity 18 (CAS 19685-11-1)
- Acipimox Impurity 9 (CAS 25594-37-0)
- 1-Ethyl-3-methyl-4-propionamido-1H-pyrazole-5-carboxamide (CAS 89257-70-5)
- 3-Ethyl-3,9-dihydro-1-propyl-8-[1-[[3-(trifluoromethyl)phenyl]methyl]-1H-pyrazol-4-yl]-1H-purine-2,6-dione (CAS 752222-83-6)
- 2-(Mercaptoamino)-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one (CAS 65062-58-0)
- 1,3-Dimethyl-5-[(dimethylamino)methylene]2,4,6-(1H,3H,5H)-tr (CAS 35824-98-7)
- (S)-2-(4-Bromophenyl)morpholine hydrochloride (CAS 1131220-34-2)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
Why CATO?
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