Estazolam Impurity 4 CAS 4547-02-8
| CAS No. | 4547-02-8 |
| Molecular Formula | C15H11ClN2S |
| Molecular Weight | 286.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Estazolam Impurity 4 (C15H11ClN2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 286.78 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Estazolam Impurity 4 (CAS 4547-02-8) is a certified pharmaceutical impurity reference standard with the molecular formula C15H11ClN2S and a molecular weight of 286.78 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Estazolam Impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H11ClN2S |
| Molecular Weight | 286.78 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Estazolam Standards
- Estazolam Impurity 6 (CAS 40678-73-7)
- Estazolam Impurity 10 (CAS 112393-62-1)
- Estazolam Impurity 9 (CAS 31709-27-0)
- Estazolam Impurity 7 (CAS 163167-55-3)
- Estazolam-D5 (CAS 170082-16-3)
- Estazolam impurity 11 (CAS 29975-18-6)
- Estazolam Impurity 5 (CAS CATO-C4X-19225)
- Estazolam Impurity 8 (CAS CATO-C4X-19228)
Recommended Standards
- 6-Chloro-2-methyl-3-phenylquinazoline-4(3H)-thione (CAS 823195-62-6)
- (5-chloro-3-pyridyl) 1H-indole-5-carboxylate (CAS 1026559-41-0)
- 5-(4-Chlorophenyl)-1-phenyl-1h-imidazole-2-thiol (CAS 852389-04-9)
- Levocetirizine Impurity 5 (CAS 109036-15-9)
- Roxadustat Impurity 41 (CAS CATO-C4X-221341)
- Dasatinib Impurity 35 (CAS CATO-C4X-160735)
- Tryptophan impurity 37 (CAS CATO-C4X-137337)
- 3-Chloro-4-ethylbenzenamine (CAS 50775-72-9)
- 1-Bromo-4-(2-bromopropyl)benzene (CAS 1310280-63-7)
- 4-(5-Methylfuran-2-yl)butan-2-amine (CAS 19509-75-2)
- 4-Isopropyl-3-propoxybenzoic acid (CAS 1361003-87-3)
- Tert-butyl 4-(3-chloropropyl)piperazine-1-carboxylate (CAS 165530-45-0)
- Allyl trifluoroacetate (CAS 383-67-5)
- D-Leu14-Tirzepatide (CAS CATO-CPTD788920)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com