4-(4-Chlorophenyl)-1-(6-fluoropyridin-2-yl)-1H-pyrazol-3-amine CAS 318284-44-5

Purity 97%+In StockPharmaceutical Standards
CAS No.318284-44-5
Molecular FormulaC14H10ClFN4
Molecular Weight288.71 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(4-Chlorophenyl)-1-(6-fluoropyridin-2-yl)-1H-pyrazol-3-amine CAS 318284-44-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 288.71 g/mol gives 4-(4-Chlorophenyl)-1-(6-fluoropyridin-2-yl)-1H-pyrazol-3-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-(4-Chlorophenyl)-1-(6-fluoropyridin-2-yl)-1H-pyrazol-3-amine (CAS 318284-44-5), molecular formula C14H10ClFN4 and molecular weight 288.71 g/mol, is a CATO reference standard with documented purity and traceability.

4-(4-Chlorophenyl)-1-(6-fluoropyridin-2-yl)-1H-pyrazol-3-amine (C14H10ClFN4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(4-Chlorophenyl)-1-(6-fluoropyridin-2-yl)-1H-pyrazol-3-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H10ClFN4
Molecular Weight288.71 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms4

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