2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperidin-4-ylidene}-N-[(phenylcarbamoyl)amino]acetamide CAS 338761-64-1
| CAS No. | 338761-64-1 |
| Molecular Formula | C20H19ClF3N5O2 |
| Molecular Weight | 453.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperidin-4-ylidene}-N-[(phenylcarbamoyl)amino]acetamide (CAS 338761-64-1) is a high-purity analytical reference standard with the molecular formula C20H19ClF3N5O2 and a molecular weight of 453.85 g/mol.
2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperidin-4-ylidene}-N-[(phenylcarbamoyl)amino]acetamide (C20H19ClF3N5O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperidin-4-ylidene}-N-[(phenylcarbamoyl)amino]acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H19ClF3N5O2 |
| Molecular Weight | 453.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related chloro Standards
- 4-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-4,5-dihydro-1H-imidazol-1-yl)benzoic acid (CAS 338412-07-0)
- 8-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3-oxo-N-phenyl-1,2,8-triazaspiro[4.5]Decane-1-carboxamide (CAS 400076-23-5)
- 2-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]sulfanyl}-N-(2-phenoxyethyl)nicotinamide (CAS 339278-11-4)
- 2-(2-((2-Chloro-7-methylquinolin-3-yl)methylene)hydrazinyl)-3-(o-tolyl)quinazolin-4(3H)-one (CAS 327039-01-0)
- 2-Chloro-N-((3-(5-ethylbenzo[d]oxazol-2-yl)phenyl)carbamothioyl)-4-fluorobenzamide (CAS 593238-52-9)
- 2-Chloro-N-((4-(5,7-dimethylbenzo[d]oxazol-2-yl)phenyl)carbamothioyl)-4-fluorobenzamide (CAS 593238-86-9)
- 4-Chloro-N-[(4-methyl-5-{[(4-nitrophenyl)methyl]sulfanyl}-4H-1,2,4-triazol-3-yl)methyl]benzene-1-sulfonamide (CAS 338421-52-6)
- 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-[(4-fluorophenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (CAS 338399-26-1)
Recommended Standards
- 1,1,2,2,3,3,4,4-octafluoro-1,4-diiodobutane 1,4-Diiodooctafluorobutane 375-50-8 (CAS 375-50-8)
- Ethyl 3-((2-(1H-indol-3-yl)ethyl)amino)-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-oxopropanoate (CAS 478258-03-6)
- 4-{[(4-bromophenyl)sulfanyl]methyl}-5-chloro-1-methyl-3-{[(4-methylphenyl)sulfanyl]methyl}-1H-pyrazole (CAS 318248-64-5)
- 3-4-6-Tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl chloride (CAS 7772-87-4)
- Fmoc-5-benzyloxy-DL-tryptophan (CAS 1219348-47-6)
- 3-(Naphthalen-2-yl)butan-1-amine (CAS 1247549-96-7)
- 6-Oxo-1-(propan-2-yl)piperidine-3-carboxylic acid (CAS 915922-33-7)
- N,N-dimethyl-3-(trifluoromethyl)piperidin-3-amine dihydrochloride (CAS 2306275-29-4)
- 3-(Isopropoxymethyl)pyrrolidine hydrochloride (CAS 1219967-48-2)
- Inhalac 120 (contains b anomer) (CAS 14641-93-1)
- 1-(3,4-dimethoxyphenyl)-2,2,2-trifluoroethan-1-amine hydrochloride (CAS 1193387-21-1)
- 4-((Methyl(thiophen-3-ylmethyl)amino)methyl)benzonitrile (CAS 1153468-48-4)
- 2,5-Dihydro-1-(2-nitrophenyl)-5-oxo-1H-1,2,4-triazole-3-carboxylic acid dimethylamide (CAS 1000574-24-2)
- (Des-Gly2)-Exenatide trifluoroacetate salt (CAS 1678416-78-8)
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