4-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-4,5-dihydro-1H-imidazol-1-yl)benzoic acid CAS 338412-07-0
| CAS No. | 338412-07-0 |
| Molecular Formula | C20H19ClF3N5O2 |
| Molecular Weight | 453.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 453.85 g/mol gives 4-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-4,5-dihydro-1H-imidazol-1-yl)benzoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-4,5-dihydro-1H-imidazol-1-yl)benzoic acid (CAS 338412-07-0), molecular formula C20H19ClF3N5O2 and molecular weight 453.85 g/mol, is a CATO reference standard with documented purity and traceability.
4-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-4,5-dihydro-1H-imidazol-1-yl)benzoic acid (C20H19ClF3N5O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-4,5-dihydro-1H-imidazol-1-yl)benzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H19ClF3N5O2 |
| Molecular Weight | 453.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Chloro Standards
- 2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperidin-4-ylidene}-N-[(phenylcarbamoyl)amino]acetamide (CAS 338761-64-1)
- 8-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3-oxo-N-phenyl-1,2,8-triazaspiro[4.5]Decane-1-carboxamide (CAS 400076-23-5)
- 2-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]sulfanyl}-N-(2-phenoxyethyl)nicotinamide (CAS 339278-11-4)
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- 2-Chloro-N-((3-(5-ethylbenzo[d]oxazol-2-yl)phenyl)carbamothioyl)-4-fluorobenzamide (CAS 593238-52-9)
- 2-Chloro-N-((4-(5,7-dimethylbenzo[d]oxazol-2-yl)phenyl)carbamothioyl)-4-fluorobenzamide (CAS 593238-86-9)
- 4-Chloro-N-[(4-methyl-5-{[(4-nitrophenyl)methyl]sulfanyl}-4H-1,2,4-triazol-3-yl)methyl]benzene-1-sulfonamide (CAS 338421-52-6)
- 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-[(4-fluorophenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (CAS 338399-26-1)
Recommended Standards
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- Ethyl 3-((2-(1H-indol-3-yl)ethyl)amino)-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-oxopropanoate (CAS 478258-03-6)
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