N-[(4-Chlorophenyl)-(2-hydroxynaphthalen-1-yl)-methyl]-acetamide CAS 332174-65-9
| CAS No. | 332174-65-9 |
| Molecular Formula | C19H16ClNO2 |
| Molecular Weight | 325.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), N-[(4-Chlorophenyl)-(2-hydroxynaphthalen-1-yl)-methyl]-acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
N-[(4-Chlorophenyl)-(2-hydroxynaphthalen-1-yl)-methyl]-acetamide (CAS 332174-65-9) is a high-purity analytical reference standard with the molecular formula C19H16ClNO2 and a molecular weight of 325.79 g/mol.
The molecular framework of N-[(4-Chlorophenyl)-(2-hydroxynaphthalen-1-yl)-methyl]-acetamide (C19H16ClNO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H16ClNO2 |
| Molecular Weight | 325.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related N Standards
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Recommended Standards
- N-(6-Chloro-2,3,4,9-tetrahydro-1H-carbazol-1-yl)picolinamide (CAS 827591-00-4)
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- N-(4-Chlorophenyl)-1-(cyanomethyl)-1,2,3,4-tetrahydroisoquinoline-2-carboxamide (CAS 338953-57-4)
- tert-Butyl (5-chloro-3-(3-(dimethylamino)acryloyl)pyridin-2-yl)carbamate (CAS 2194550-33-7)
- 2-Amino-2-[5-[5-(3-chloro-4-propoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-benzofuranyl]-1,3-propanediol (CAS 1220973-37-4)
- 3-bromo-4-chloro-1-[(4-methoxyphenyl)methyl]pyrazolo[3,4-b]pyridine (CAS 1854056-69-1)
- (R)-1-(1,3-Dimethyl-1h-pyrazol-4-yl)ethan-1-amine (CAS 1568076-46-9)
- 2-((3-Chlorobenzyl)thio)-3-(4-methoxyphenyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 477333-56-5)
- 4-(Bromomethyl)-3,5-difluorobenzonitrile (CAS 1239964-16-9)
- methyl (4S)-2-oxooxazolidine-4-carboxylate (CAS 132682-22-5)
- 4-Bromo-N-(3-methoxyphenethyl)-N-phenylbenzamide 96718-92-2 (CAS 96718-92-2)
- 5-Bromo-3-iodo-2-methylbenzoic acid methyl ester, 97% (CAS 1378861-84-7)
- Atrasentan Impurity 29 (CAS 1058392-69-0)
- Palmitoyl Tripeptide-1 TFA salt (CAS 2803375-47-3)
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