Vortioxetine Impurity 112 CAS 33264-60-7
| CAS No. | 33264-60-7 |
| Molecular Formula | C14H15NS |
| Molecular Weight | 229.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Vortioxetine Impurity 112 (C14H15NS) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Vortioxetine Impurity 112 (CAS 33264-60-7), a pharmacopoeial impurity reference standard (molecular formula C14H15NS, MW 229.34 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H15NS |
| Molecular Weight | 229.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Vortioxetine Standards
- Vortioxetine Impurity 111 (CAS 640767-44-8)
- Vortioxetine Impurity 143 (CAS CATO-C4X-1056143)
- Vortioxetine Impurity 163 (CAS CATO-C4X-1056164)
- Vortioxetine Impurity 59 (CAS 900641-61-4)
- Vortioxetine Impurity 89 (CAS 1019453-85-0)
- Vortioxetine Impurity 44 (CAS CATO-C4X-105644)
- Vortioxetine Impurity 73 (CAS 66698-28-0)
- Vortioxetine Impurity 2 (CAS 1011-13-8)
Recommended Standards
- 2-Amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid ethyl ester 2-amino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid ethyl ester 2-amino-4,5,6,7-tetrahydrobenzo(b)thiophene-3-carboxylic acid ethyl ester ethyl 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate 2-amino-3-ethoxycarbonyl-thienocyclohexane ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate benzo[b]thiophene-3-carboxylic acid, 2-amino-4,5,6,7-tetrahydro-, ethyl ester ethyl-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 2-amino-4,5,6,7-tetrahydro-benzo[b] thiophene-3-carboxylic acid ethyl ester ethyl2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 4506-71-2 (CAS 4506-71-2)
- Ticlopidine EP Impurity D (CAS 55142-78-4)
- tert-Butyl 6-mercapto-2-azaspiro[3.3]heptane-2-carboxylate (CAS 2803862-38-4)
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- Tetrabenazine Impurity 60 (CAS 2608769-99-7)
- 5-(methanesulfonylmethyl)-2-methoxyaniline hydrochloride (CAS 1803593-30-7)
- 1-(2-Chlorophenyl)pyrrolidine-2,5-dione (CAS 7402-22-4)
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- 2,3-Diamino-5-bromophenol (CAS 1628908-26-8)
- Ethyl 2-(3-((tert-butoxycarbonyl)amino)piperidin-2-yl)acetate (CAS 215306-00-6)
- 3,5-Dimethyl-1-(1,3-dioxolan-2-ylmethyl)benzene (CAS 898759-42-7)
- Neuropeptide FF (CAS 99566-27-5)
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