Vortioxetine Impurity 143 CAS CATO-C4X-1056143
| CAS No. | CATO-C4X-1056143 |
| Molecular Formula | C14H15NS |
| Molecular Weight | 229.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Vortioxetine Impurity 143.
As a process- or degradation-related impurity, Vortioxetine Impurity 143 (CAS CATO-C4X-1056143, C14H15NS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, Vortioxetine Impurity 143 is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 229.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Vortioxetine Impurity 143 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H15NS |
| Molecular Weight | 229.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Vortioxetine Standards
- Vortioxetine Impurity 111 (CAS 640767-44-8)
- Vortioxetine Impurity 112 (CAS 33264-60-7)
- Vortioxetine Impurity 163 (CAS CATO-C4X-1056164)
- Vortioxetine Impurity 59 (CAS 900641-61-4)
- Vortioxetine Impurity 89 (CAS 1019453-85-0)
- Vortioxetine Impurity 44 (CAS CATO-C4X-105644)
- Vortioxetine Impurity 73 (CAS 66698-28-0)
- Vortioxetine Impurity 2 (CAS 1011-13-8)
Recommended Standards
- 2-Amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid ethyl ester 2-amino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid ethyl ester 2-amino-4,5,6,7-tetrahydrobenzo(b)thiophene-3-carboxylic acid ethyl ester ethyl 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate 2-amino-3-ethoxycarbonyl-thienocyclohexane ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate benzo[b]thiophene-3-carboxylic acid, 2-amino-4,5,6,7-tetrahydro-, ethyl ester ethyl-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 2-amino-4,5,6,7-tetrahydro-benzo[b] thiophene-3-carboxylic acid ethyl ester ethyl2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 4506-71-2 (CAS 4506-71-2)
- Ticlopidine EP Impurity D (CAS 55142-78-4)
- (2R)-1-(tert-Butyldimethylsilyl)-4-oxoazetidine-2-carboxylic acid (CAS 162856-35-1)
- tert-Butyl 6-mercapto-2-azaspiro[3.3]heptane-2-carboxylate (CAS 2803862-38-4)
- Ranitidine Hydrochloride EP Impurity F (CAS 81074-81-9)
- Orforglipron impurity 71 (CAS CATO-C4X-323471)
- Iomeprol Impurity 6 (CAS CATO-C4X-18206)
- 6-Amino-1-(2-(dimethylamino)ethyl)-5,6,7,8-tetrahydroquinolin-2(1H)-one (CAS 1422142-17-3)
- 1-Chloro-3-(difluoromethyl)-2-methoxybenzene (CAS 943830-41-9)
- 3-(Aminomethyl)-4-(methylamino)phenol (CAS 1243414-22-3)
- 2-(Difluoromethyl)-6-hydroxy-3-methylpyridine-4-carboxaldehyde (CAS 1806977-25-2)
- 1-(4-amino-1H-pyrazol-1-yl)-2-methylpropan-2-ol (CAS 1206640-59-6)
- Benzyl(3-bromo-2-chlorophenyl)sulfane (CAS 1182728-20-6)
- Human IgE Pentapeptide HEPP (CAS 62087-72-3)
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