N-(4-chlorophenyl)-2-((3-cyano-4-(4-methoxyphenyl)-6-phenylpyridin-2-yl)thio)acetamide CAS 334497-74-4
| CAS No. | 334497-74-4 |
| Molecular Formula | C27H20ClN3O2S |
| Molecular Weight | 485.98 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
N-(4-chlorophenyl)-2-((3-cyano-4-(4-methoxyphenyl)-6-phenylpyridin-2-yl)thio)acetamide (CAS 334497-74-4) is a high-purity analytical reference standard with the molecular formula C27H20ClN3O2S and a molecular weight of 485.98 g/mol.
The molecular framework of N-(4-chlorophenyl)-2-((3-cyano-4-(4-methoxyphenyl)-6-phenylpyridin-2-yl)thio)acetamide (C27H20ClN3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H20ClN3O2S |
| Molecular Weight | 485.98 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- 3-((4-Chlorophenyl)sulfonyl)-N-(4-ethoxyphenyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-amine (CAS 892738-55-5)
- Ethyl 2-(4-(4-chlorophenyl)piperazin-1-yl)-4,5-diphenyl-1H-pyrrole-3-carboxylate (CAS 400081-89-2)
- 4-((4-Chlorophenyl)thio)-2-phenyl-N-(3-(trifluoromethyl)phenyl)pyrimidine-5-carboxamide (CAS 400076-30-4)
- 2-((5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(4-iodo-2-methylphenyl)acetamide (CAS 332904-32-2)
- 1-(4-Chlorophenyl)-3-{3-[(4-chlorophenyl)sulfanyl]-5-(trifluoromethyl)pyridine-2-carbonyl}urea (CAS 338759-10-7)
- 3-(4-Chlorophenyl)-1-(2-nitro-4-(trifluoromethyl)phenyl)-6-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine (CAS 338770-83-5)
- N-(((4-chlorophenyl)carbamoyl)oxy)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 861208-34-6)
- 3-(4-Chlorophenyl)-N-(3-(imidazo[1,2-a]pyridin-2-yl)phenyl)-3-(2,2,2-trifluoroacetamido)propanamide (CAS 866039-29-4)
Recommended Standards
- 3-Chloro-N-cyclohexyl-N-(2-((2-methyl-5-nitrophenyl)amino)-2-oxoethyl)benzo[b]thiophene-2-carboxamide (CAS 332156-43-1)
- tert-Butyl (1-(4-(5-chloro-3-phenyl-1,6-naphthyridin-2-yl)phenyl)cyclobutyl)carbamate (CAS 1032349-99-7)
- 3-Amino-N-(5-chloro-2-methoxyphenyl)-4,6-diphenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332160-52-8)
- 3-Amino-N-(4-chlorophenyl)-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 334497-87-9)
- Ethyl 5-(3-iodophenyl)isoxazole-4-carboxylate (CAS 887407-86-5)
- 1-(2-(Diethylamino)ethyl)-3-hydroxy-5-(4-hydroxy-3-methoxyphenyl)-4-(4-isopropoxy-3-methylbenzoyl)-1H-pyrrol-2(5H)-one (CAS 371233-37-3)
- 7-Chloro-3-propylquinolin-2-amine (CAS 948294-11-9)
- 6-Chloro-4-methylnicotinonitrile (CAS 66909-35-1)
- Cefotaxime Impurity 73 (CAS CATO-C4X-120173)
- 1H-imidazol-2-ylmethanethiol (CAS 53062-94-5)
- 2-[(2-Chloroethyl)amino]ethyl benzoate HCl (CAS 100129-68-8)
- (6-Bromo-pyridin-3-yl)-methanol (CAS 122306-01-8)
- 1-(2-Nitrophenyl)-1,2,4-triazole (CAS 25688-22-6)
- D-Ala18-Tirzepatide (CAS CATO-CPTD788916)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com